64205-06-7

Basic information

• Product Name: Benzeneacetyl chloride, a-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-, (R)-
• CAS NO: 64205-06-7
• Molecular Formula: C15H16ClN3O4
• Molecular Weight: 337.763
• Mol File: 64205-06-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetyl chloride, a-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetyl chloride, a-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-, (R)-(64205-06-7)
• EPA Substance Registry System: Benzeneacetyl chloride, a-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-, (R)-(64205-06-7)

Safety Data

• Hazardous Substances Data: 64205-06-7(Hazardous Substances Data)

Upstream product

• 63422-71-9 (R)-α-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic acid 

Downstream Products

• 1407155-93-4 C₃₁H₃₂ClN₉O₆S 
• 86062-39-7 sodium 7β--2-phenylacetamido>-7α-formamido-cephalosporanate 
• 86062-38-6 t-butyl 7β--2-phenylacetamido>-7α-formamidocephalosporanate 
• 86062-37-5 t-butyl 7α-amino-7β--2-phenylacetamido>cephalosporanate 
• 137839-94-2 Sodium 6β-<(2R)-2-(4-Ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-2-phenylacetamido>-6α-vinylpenicillanate 
• 137839-99-7 Allyl 6β-<(2R)-2-(4-Ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-2-phenylacetamido>-6α-succinimidopenicillanate 
• 137840-00-7 Allyl 6β-<(2R)-2-(4-Ethyl-2,3-dioxopiperazin-1-ylcarbonylamino)-2-phenylacetamido>-6α-mercaptopenicillanate 
• 74529-26-3 (6R,7R) and (6S,7S)-7-<2R-2(4-ethyl-2,3-dioxo-1-piperidinyl)formamido>-3-trifluoromethyl-3-cephem-4-carboxylic acid (1:1 mixture) 

Relevant articles and documents

Synthesis and biological activity of 3-(N-substituted pyridinium-4-thiomethyl)-7α-formamido cephalosporins

The synthesis and antibacterial activity of a series of 3-(1-substituted pyridinium-4-thiomethyl)-7α-formamido cephalosporins is described. All the derivatives showed good potency and stability to bacterial β-lactamases. The antibacterial efficacy seen with the N-alkyl pyridinium substituents was enhanced by the introduction of a catecholic side chain at C-7 and by preparation of N-(substituted amino)pyridinium derivatives.

Further Synthetic Studies in Penicillin C(6)-Substitution Including the Versatile 6&α-Succinimidooxy Leaving Group

Treatment of benzyl 6α-dimethylamino-6β-phenoxyacetamidopenicillanate 3 with methyl iodide led, in the absence of added nucleophiles, to the oxygen-bridged dimer 8 via adventitious water present.Added methanol or water led to the 6α-methoxy or -hydroxy pr