64206-63-9Relevant academic research and scientific papers
The Reaction between Diazoalkanes and Allylic Halides Carrying Electronegative γ-Substituents. 4. Conformational Equilibria of Highly Substituted 1-Pyrazolines
Gulbrandsen, Trygve,Kolsaker, Per
, p. 219 - 226 (2007/10/02)
Some di- and trisubstituted 1-pyrazoline-3-carbonitriles were synthesized and the coupling constants between vicinal protons were measured.In those cases where only one large substituent is present, the pseudoequatorial position is preferred.When two large groups are present trans to each other in vicinal position, the dipseudoaxial conformation is preferred.The compounds with preference for the dipseudoaxial conformation unexpectedly gave only cyclopropane derivatives when decomposed.
