642071-29-2

Upstream product

• 5459-04-1 ethane-1,2-diylbis(3-oxobutanoate) 
• 2028-74-2 p-chlorobenzenediazonium chloride 
• 642071-26-9 2-chloro-3-oxo-butyric acid 2-(2-chloro-3-oxo-butyryloxy)-ethyl ester 

Relevant academic research and scientific papers

Synthesis of bis-(3,5)pyrazolophanes via double cycloadditive macrocyclisation

Double cycloadditive macrocyclisation of bis-hydrazonoyl chlorides 5 were performed with bis-allyl ethers 9 and 10, bis-vinyl ether 14 and bis-propargyl ether 18. The title compounds having a 18-, 19-, 22- or 24- membered ring annulated to the pyrazole units were obtained with good overall yield.