642089-90-5

Upstream product

• 170997-51-0 methyl 2-amino-2-deoxy-3,4;5,6-di-O-isopropylidene-D-gluconate 
• 1623-92-3 4-phenoxyphenylsulfonyl chloride 
• 642089-89-2 (2R,4'S,4R,5R)-(4-phenoxybenzenesulfonylamino)-[2',2',2,2-tetramethyl-[4',4]bi([1,3]dioxolanyl)-5'-yl]acetic acid methyl ester 

Downstream Products

• 642089-93-8 (3aR,4R,7R,7aR)-7-hydroxy-2,2-dimethyl-5-(4'-phenoxybenzenesulfonyl)hexahydro[1,3]dioxolo[4,5-c]-4-carboxylic acid benzyloxyamide 
• 642089-94-9 (2R,3R,4R,5R)-3,4,5-trihydroxy-1-(4'-phenoxybenzenesulfonyl)-piperidine-2-carboxylic acid benzyloxyamide 
• 642089-92-7 (3aR,4R,7R,7aR)-7-hydroxy-2,2-dimethyl-5-(4'-phenoxybenzenesulfonyl)hexahydro[1,3]dioxolo[4,5-c]-4-carboxylic acid methyl ester 
• 642089-91-6 (1S,2R,4'R,5'S)-[5'-(1-hydroxy-2-methanesulfonyloxyethyl)-2',2'-dimethyl[1,3]dioxolan-4'-yl]-(4-phenoxybenzenesulfonylamino)acetic acid methyl ester 

Relevant academic research and scientific papers

NOVEL AZASUGAR DERIVATIVE AND DRUG CONTAINING THE SAME AS THE ACTIVE INGREDIENT

A novel azasugar derivative, and a drug containing the same as an active ingredient are disclosed. The drug is useful for treatment of keratinocyte-proliferative diseases.

Azasugar-Based MMP/ADAM Inhibitors as Antipsoriatic Agents

As a part of synthetic studies on MMP (matrix metalloproteinase)/ADAM (a disintegrin and metalloproteinase) inhibitors, we have preliminarily communicated that azasugar-based compound 1a exhibited a potential inhibitory activity on some metalloprotease-ca