642093-52-5

Basic information

• Product Name: Benzene, 1-[(1E)-2-bromoethenyl]-4-(1-methylethyl)-
• CAS NO: 642093-52-5
• Molecular Formula: C11H13Br
• Molecular Weight: 225.128
• Mol File: 642093-52-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzene, 1-[(1E)-2-bromoethenyl]-4-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-[(1E)-2-bromoethenyl]-4-(1-methylethyl)-(642093-52-5)
• EPA Substance Registry System: Benzene, 1-[(1E)-2-bromoethenyl]-4-(1-methylethyl)-(642093-52-5)

Safety Data

• Hazardous Substances Data: 642093-52-5(Hazardous Substances Data)

Upstream product

• 142521-08-2 1,1-dibromo-2-(4-isopropylphenyl)ethene 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 3368-21-6 4-isopropylcinnamic acid 
• 3368-21-6 (E)-4-isopropylcinnamic acid 

Downstream Products

• 1421606-80-5 (E)-8-chloro-N-(4-isopropylstyryl)-4-methoxyquinoline-2-carboxamide 
• 1857-74-5 2,3-diphenylbutane 

Relevant articles and documents

Selective Rhodium-Catalyzed Hydroformylation of Terminal Arylalkynes and Conjugated Enynes to (Poly)enals Enabled by a π-Acceptor Biphosphoramidite Ligand

The hydroformylation of terminal arylalkynes and enynes offers a straightforward synthetic route to the valuable (poly)enals. However, the hydroformylation of terminal alkynes has remained a long-standing challenge. Herein, an efficient and selective Rh-catalyzed hydroformylation of terminal arylalkynes and conjugated enynes has been achieved by using a new stable biphosphoramidite ligand with strong π-acceptor capacity, which affords various important E-(poly)enals in good yields with excellent chemo- and regioselectivity at low temperatures and low syngas pressures.

Stereoselective synthesis of (E)-β-arylvinyl bromides by microwave-induced Hunsdiecker-type reaction

(E)-β-Arylvinyl bromides were readily prepared in a short reaction time (1-2 min) by microwave irradiation of the corresponding 3-arylpropenoic acids in the presence of N-bromosuccinimide and a catalytic amount of lithium acetate. Furthermore, two facile strategies for the efficient synthesis of (E)-β-bromo-4-arylethynylstyrene and (E)-β-bromo-4-arylstyrene have been developed by respectively combining Sonogashira and Suzuki coupling reaction with Hunsdiecker-type reaction. Formation of cis-α-bromo-β- lactone by microwave irradiation of cis-cinnamic acid with NBS provides a useful support for the mechanistic study of the present halodecarboxylation reaction. Georg Thieme Verlag Stuttgart.