64224-67-5Relevant academic research and scientific papers
NOVEL CYCLIC COMPOUND HAVING PYRIMIDINYLALKYLTHIO GROUP
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Page/Page column 16, (2008/06/13)
The present invention has its object to study synthesis of novel cyclic compounds having a pyrimidinylalkylthio group and to find pharmacological actions of the compounds. According to the present invention, a compound represented by the formula (1) or a
Process for producing 2-substituted thiopyrimidine-4-carboxylate
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, (2008/06/13)
There is disclosed a process for producing a 2-substituted thiopyrimidine-4-carboxylate represented by the formula (3): wherein R2 represents a substituted or unsubstituted hydrocarbon group and R3 represents a hydrocarbon group, which comprises reacting an α-keto ester compound represented by the formula (1): R1OCH═CHCOCO2R2??(1) wherein R1 represents a substituted or unsubstituted hydrocarbon group, and R2 has the same meaning as defined above, with an isothiourea compound represented by the formula (2): wherein R3 has the same meaning as defined above.
