64271-00-7

Usage

Uses

Used in Pharmaceutical Industry:
1-(5-methyl-2-furyl)propan-1-amine is used as a pharmaceutical intermediate for the synthesis of various drugs, leveraging its unique chemical structure to facilitate the creation of new medicinal compounds.
Used in Agrochemical Production:
In the agrochemical sector, 1-(5-methyl-2-furyl)propan-1-amine serves as a key component in the production of various agricultural chemicals, contributing to the development of effective pest control and crop protection solutions.
Used in Organic Synthesis:
As a precursor in organic synthesis, 1-(5-methyl-2-furyl)propan-1-amine is utilized to initiate or facilitate complex chemical reactions, leading to the formation of a wide range of organic compounds.
Used in Medicinal Chemistry and Drug Discovery:
Due to its structural properties and reactivity, 1-(5-methyl-2-furyl)propan-1-amine is employed in the field of medicinal chemistry and drug discovery, where it aids in the exploration and development of novel therapeutic agents.

Upstream product

• 133712-93-3 1-(5-methyl-[2]furyl)-propan-1-one oxime 
• 534-22-5 2-methylfuran 
• 102022-21-9 N-(5-methylfurfurylidene)-N-(diphenylmethyl)amine 
• 60942-20-3 1-(5-methylfuran-2-yl)propan-1-ol 
• 620-02-0 5-Methylfurfural 
• 1099823-22-9 5-methyl-2-propionylfuran 
• 10599-69-6 5-methyl-2-propionylfuran 

Downstream Products

• 2364-75-2 emoxypine 
• 780760-09-0 (R)-1-(5-methyl-furan-2-yl)-propylamine D-tartarate 
• 1393117-44-6 4-methyl-N-[1-(5-methylfuran-2-yl)propyl]benzenesulfonamide 
• 473727-49-0 C₂₁H₂₃N₃O₅ 
• 478264-01-6 5-methyl-N-[1-(5-methylfuran-2-yl)-propyl]-2-nitrobenzamide 

Relevant academic research and scientific papers

Manganese=Catalyzed Achmatowicz Rearrangement Using Green Oxidant H2O2

Oxidation reactions have been extensively studied in the context of the transformations of biomass=derived furans. However, in contrast to the vast literature on utilizing the stoichiometric oxidants, such as m=CPBA and NBS, catalytic methods for the oxidative furan=recyclizations remain scarcely investigated. Given this, we report a means of manganese=catalyzed oxidations of furan with low loading, achieving the Achmatowicz rearrangement in the presence of hydrogen peroxide as an environmentally benign oxidant under mild conditions with wide functional group compatibility.

Alkylative Amination of Biogenic Furans through Imine-to-Azaallyl Anion Umpolung

Starting from biogenic furfurals, an operationally simple and scalable condensation-umpolung-alkylation protocol was employed in the synthesis of racemic furfurylamines. Subsequent enzymatic kinetic resolution by ω-transaminase or lipase biocatalysts allows for the preparation of functionalized heterocyclic building blocks from biogenic base chemicals in optically pure form.

PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 1,2-SUBSTITUTED 3,4-DIOXO-1-CYCLOBUTENE COMPOUNDS

This application discloses a novel process for the preparation of 1.2 - substituted 3, 4 - dioxo - 1 - cyclobutene compounds of formula (A), which have utility, for example, in the treatment of CXC chemokine -mediated diseases, and intermediates useful in the synthesis thereof.

Anthranilamides and methods of their use

The present invention is related to anthranilamides of formula I, in which R(1) to R(7) have the meanings indicated herein, a process for their preparation, their use as medicaments, and pharmaceutical preparations containing them. The compounds act on the Kv1.5 potassium channel and inhibit a potassium current which is referred to as the ultra-rapidly activating delayed rectifier in the atrium of the human heart. The compounds are therefore suitable for use as novel antiarrhythmic agents for the treatment and prophylaxis of atrial arrhythmias (e.g., atrial fibrillation (AF) or atrial flutter).