64271-30-3Relevant academic research and scientific papers
New Derivatives of Kanamycin B Obtained by Modifications and Substitutions in Position 6''. 1. Synthesis and Microbiological Evaluation
Schepdael, A. Van,Delcourt, J.,Mulier, M.,Busson, R.,Verbist, L.,et al.
, p. 1468 - 1475 (2007/10/02)
The clinical use of the potent, wide-spectrum aminoglycoside antibiotics is limited by oto- and nephrotoxicities.The latter is related to the binding of these polycationic drugs to negatively charged phospholipids and to the subsequent inhibition of lysos
