64297-91-2

Basic information

• Product Name: 2-CHLORO-N-(3-PHENYL-PROPYL)-ACETAMIDE
• Synonyms: 2-chloro-N-(3-phenylpropyl)ethanamide
• CAS NO: 64297-91-2
• Molecular Formula: C₁₁H₁₄ClNO
• Molecular Weight: 211.69
• Mol File: 64297-91-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 387.4°C at 760 mmHg
• Flash Point: 188.1°C
• Appearance: /
• Density: 1.119g/cm³
• Vapor Pressure: 3.31E-06mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: 2-CHLORO-N-(3-PHENYL-PROPYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-N-(3-PHENYL-PROPYL)-ACETAMIDE(64297-91-2)
• EPA Substance Registry System: 2-CHLORO-N-(3-PHENYL-PROPYL)-ACETAMIDE(64297-91-2)

Safety Data

• Hazardous Substances Data: 64297-91-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14ClNO/c12-9-11(14)13-8-4-7-10-5-2-1-3-6-10/h1-3,5-6H,4,7-9H2,(H,13,14)

Upstream product

• 2038-57-5 3-Phenylpropan-1-amine 
• 79-04-9 chloroacetyl chloride 
• 107-07-3 2-chloro-ethanol 

Relevant articles and documents

Oxidative Amide Coupling from Functionally Diverse Alcohols and Amines Using Aerobic Copper/Nitroxyl Catalysis

The aerobic Cu/ABNO catalyzed oxidative coupling of alcohols and amines is highlighted in the synthesis of amide bonds in diverse drug-like molecules (ABNO=9-azabicyclo[3.3.1]nonane N-oxyl). The robust method leverages the privileged reactivity of alcohol

Compounds with cardiac myosin activating function and pharmaceutical composition containing the same for treating or preventing heart failure

The present invention relates to a compound having a cardiotonic activating function and a pharmaceutical composition containing the same. The composition comprising the compound according to the present invention is effective in preventing or treating heart failure. In addition, the compound is represented by chemical formula 2 or is pharmaceutically acceptable salt thereof.COPYRIGHT KIPO 2016

Modulating the development of E. coli biofilms with 2-aminoimidazoles

The synthesis of a 20 member 2-aminoimidazole/triazole pilot library is reported. Each member of the library was screened for its ability to inhibit or promote biofilm development of either Escherichia coli and Acinetobacter baumannii. From this screen, E. coli-selective 2-aminoimidazoles were discovered, with the best inhibitor inhibiting biofilm development with an IC50 of 13 μM. The most potent promoter of E. coli biofilm formation promoted biofilm development by 321% at 400 μM.