64299-23-6Relevant articles and documents
2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a new scaffold to obtain potent and selective human a3 adenosine receptor antagonists: new insights into the receptor-antagonist recognition
Lenzi, Ombretta,Colotta, Vittoria,Catarzi, Daniela,Varano, Flavia,Poli, Daniela,Filacchioni, Guido,Varani, Katia,Vincenzi, Fabrizio,Borea, Pier Andrea,Paoletta, Silvia,Morizzo, Erika,Moro, Stefano
experimental part, p. 7640 - 7652 (2010/08/03)
A molecular simplification approach of previously reported 2-arylpyrazolo[3,4-c]quinolin-4-ones was applied to design 2-arylpyrazolo[4,3-d] pyrimidin-7-one derivatives as new human A3 adenosine receptor antagonists. Substituents with different