643013-63-2Relevant academic research and scientific papers
New building blocks for the assembly of sequence selective molecular zippers.
Hunter, Christopher A,Jones, Philip S,Tiger, Pascale M N,Tomas, Salvador
, p. 1642 - 1643 (2003)
Synthetic H-bonded molecular zippers contain no sequence information that can be used to engineer the selective binding interactions characteristic of biopolymers; reversing the sense of the amide bonds in the two binding partners generates a new orthogonal recognition motif and the mutually complementary binding partners form complexes an order of magnitude more stable than the corresponding mismatch complexes.
