643036-38-8

Basic information

• Product Name: (S)-4-Benzyl-3-((R)-2,4-dimethyl-pent-4-enoyl)-oxazolidin-2-one
• Synonyms: (S)-4-Benzyl-3-((R)-2,4-dimethyl-pent-4-enoyl)-oxazolidin-2-one
• CAS NO: 643036-38-8
• Molecular Weight: 287.359
• Mol File: 643036-38-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-Benzyl-3-((R)-2,4-dimethyl-pent-4-enoyl)-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Benzyl-3-((R)-2,4-dimethyl-pent-4-enoyl)-oxazolidin-2-one(643036-38-8)
• EPA Substance Registry System: (S)-4-Benzyl-3-((R)-2,4-dimethyl-pent-4-enoyl)-oxazolidin-2-one(643036-38-8)

Safety Data

• Hazardous Substances Data: 643036-38-8(Hazardous Substances Data)

Upstream product

• 3756-30-7 1-iodo-2-methyl-2-propene 
• 131685-53-5 (S)-4-benzyl-3-propionyl-2-oxazolidinone 

Downstream Products

• 643036-63-9 (S)-4-Benzyl-3-[(2R,4R)-5-(tert-butyl-dimethyl-silanyloxy)-2,4-dimethyl-pentanoyl]-oxazolidin-2-one 
• 887137-74-8 tert-Butyl-[2,4-dimethoxy-3-methyl-6-[(2R,5S,6R)-5-methyl-4-methylene-6-((S)-3-methyl-pent-4-enyl)-[1,3]dioxan-2-yl]-5-((3S,5S)-3,5,7-trimethyl-oct-7-en-1-ynyl)-phenoxy]-dimethyl-silane 
• 887137-73-7 (2R,5S,6R)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-3,5-dimethoxy-4-methyl-6-((3S,5S)-3,5,7-trimethyl-oct-7-en-1-ynyl)-phenyl]-5-methyl-6-((S)-3-methyl-pent-4-enyl)-[1,3]dioxan-4-one 
• 887137-72-6 2-(tert-Butyl-dimethyl-silanyloxy)-3,5-dimethoxy-4-methyl-6-((3S,5S)-3,5,7-trimethyl-oct-7-en-1-ynyl)-benzaldehyde 
• 853996-03-9 (2S,4S)-2,4,6-Trimethyl-hept-6-enoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide 
• 643036-60-6 (S)-4-Benzyl-3-((2R,4R)-5-hydroxy-2,4-dimethyl-pentanoyl)-oxazolidin-2-one 
• 74034-73-4 (3R,5S)-3,5-dimethyltetrahydro-2H-pyran-2-one 

Relevant articles and documents

Evolution of a total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis strategy

A convergent stereocontrolled total synthesis of (-)-kendomycin (1) has been achieved. The synthesis proceeds with a longest linear sequence of 21 steps, beginning with commercially available 2,4-dimethoxy-3-methylbenzaldehyde (12). Highlights of the synthesis include an effective Petasis-Ferrier union/rearrangement tactic to construct the sterically encumbered tetrahydropyran ring, a ring-closing metathesis to generate the C(4a-13-20a) macrocycle, an effective epoxidation/deoxygenation sequence to isomerize the C(13,14) olefin, and a biomimetic quinone-methide-lactol assembly to complete the synthesis.