643070-34-2

Upstream product

• 643068-20-6 (1R,4S,5R)-4-bromo-6-oxabicyclo[3.2.1]octan-7-one 
• 643070-24-0 (1R,3R,4R)-4-azido-3-hydroxy-cyclohexanecarboxylic acid methyl ester 
• 643070-27-3 C₈H₁₅NO₃ 
• 615569-02-3 methyl (1α,3α,4β)-4-[(tert-butoxycarbonyl)amino]-3-hydroxycyclohexanecarboxylate 
• 643070-30-8 methyl (1α,3β,4β)-4-[(tert-butoxycarbonyl)amino]-3-methoxycyclohexanecarboxylate 
• 5709-98-8 (R)-cyclohex-3-enecarboxylic acid 
• 643070-22-8 (1R,3R,4S)-4-bromo-3-hydroxy-cyclohexanecarboxylic acid methyl ester 
• 643070-32-0 (1R,3R,4R)-4-tert-butoxycarbonylamino-3-methoxy-cyclohexanecarboxylic acid 

Downstream Products

• 643070-36-4 [(1R,2R,4R)-2-methoxy-4-(2-methyl-quinolin-8-ylcarbamoyl)-cyclohexyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases

As part of our wider efforts to exploit novel mode of action antibacterials, we have discovered a series of cyclohexyl-amide compounds that has good Gram positive and Gram negative potency. The mechanism of action is via inhibition of bacterial topoisomer

ANTIBACTERIAL COMPOUNDS

Cyclohexane and cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man