643094-08-0

Basic information

• Product Name: Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate
• Synonyms: 4-(Methoxycarbonyl)naphthalene-1-boronic acid, pinacol ester;Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate
• CAS NO: 643094-08-0
• Molecular Formula: C₁₈H₂₁BO₄
• Molecular Weight: 312.16794
• Mol File: 643094-08-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerated.
• CAS DataBase Reference: Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate(643094-08-0)
• EPA Substance Registry System: Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate(643094-08-0)

Safety Data

• Hazardous Substances Data: 643094-08-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate is used as a reagent in organic synthesis for the formation of carbon-carbon and carbon-heteroatom bonds. Its boron-containing structure facilitates reactions such as Suzuki-Miyaura cross-coupling, which is crucial for the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate is used as a key intermediate in the synthesis of various drugs. Its ability to form carbon-carbon and carbon-heteroatom bonds makes it a valuable component in the development of new pharmaceutical compounds with diverse therapeutic applications.
Used in Agrochemical Industry:
Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate is also utilized in the agrochemical industry as a building block for the synthesis of agrochemicals. Its role in forming essential bonds contributes to the development of effective pesticides, herbicides, and other agricultural chemicals that protect crops and enhance agricultural productivity.
Used in Material Science:
In the field of material science, Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoate is employed in the synthesis of advanced materials with specific properties. Its involvement in bond formation allows for the creation of materials with tailored characteristics, such as improved stability, reactivity, or selectivity, for various applications in industries like electronics, coatings, and polymers.

Upstream product

• 35615-97-5 4-bromo-naphthalene-1-carboxylic acid methyl ester 
• 73183-34-3 bis(pinacol)diborane 
• 16650-55-8 4-bromonaphthalene-1-carboxylic acid 

Relevant articles and documents

A Porous Zirconium-Based Metal-Organic Framework with the Potential for the Separation of Butene Isomers

By using a novel C3-symmetrical tricarboxylate (4,4′,4′′-benzene-1,3,5-triyl-1,1′,1′′-trinaphthoic acid), a novel zirconium-based metal-organic framework ZJNU-30 was solvothermally synthesized and structurally characterized. Single-crystal X-ray structural analyses show that ZJNU-30 consists of Zr6-based nodes connected by the organic linkers to form a (3,8)-connected network featuring the coexistence of two different polyhedral cages: octahedral and cuboctahedral cages with the dimensions of about 14 and 22 ?, respectively. Remarkably, ZJNU-30 is very stable when exposed to air for one month. More importantly, with a moderately high surface area, hierarchical pore structures, and an aromatic-rich pore surface in the framework, ZJNU-30, after activation, exhibits a promising potential for the selective adsorptive separation of industrially important butene isomers consisting of cis-2-butene, trans-2-butene, 1-butene, and iso-butene at ambient temperature. This separation was established exclusively by gas adsorption isotherms and simulated breakthrough experiments. To the best of our knowledge, this is the first study investigating porous metal-organic frameworks for butene-isomer separation.

AMINOALCOHOL DERIVATIVES

The present invention relates to a compound formula [I]: wherein Y is bond,--O--(CH2)n--(in which n is 1, 2, 3 or 4), etc., Z is cyano, tetrazolyl, etc., R1 is hydrogen, lower alkyl, etc., R2 is hydrogen or an amino protective group, R3 is hydrogen or lower alkyl, R4 is hydrogen or lower alkyl, R5 and R8 are each independently hydrogen, halogen, hydroxy, lower alkyl, etc., R6 is hydrogen, lower alkyl, etc., R9 is hydrogen or lower alkyl, and i is 1 or 2, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.