64328-63-8Relevant academic research and scientific papers
1-substituted benzoyl-4-fatty acyl semicarbazide derivative, preparation method and application thereof as antibacterial agent
-
Paragraph 0138; 0139; 0141, (2018/09/14)
The invention belongs to the technical field of antibacterial agents, and relates to a 1-substituted benzoyl-4-fatty acyl semicarbazide derivative, a preparation method and application thereof as an antibacterial agent. The compound is shown in a formula
Tuning the self-assembly and photophysical properties of bi-1,3,4-thiadiazole derivatives through electron donor-acceptor interactions and their application in OLEDs
Yadav, Abhay Kumar,Pradhan, Balaram,Ulla, Hidayath,Nath, Subrata,De, Joydip,Pal, Santanu Kumar,Satyanarayan,Achalkumar, Ammathnadu S.
supporting information, p. 9345 - 9358 (2017/09/29)
We report several shape anisotropic molecules that contain two centrally placed 1,3,4-thiadiazole units, which vary from each other with respect to the number and length of the flexible chains at the termini. The number, position and length of the periphe
Synthesis and anticonvulsant activity evaluation of 4-butyl-5-(4- alkoxyphenyl)-2H-1,2,4-triazole-3(4H)-ones
Zhu, Zi-Shi,Wang, Shi-Ben,Deng, Xian-Qing,Liu, Da-Chuan,Quan, Zhe-Shan
, p. 628 - 635 (2014/05/20)
A series of 4-butyl-5-(4-alkoxyphenyl)-2H-1,2,4-triazole-3(4H)-ones (6a-6u) was designed and synthesized. The anticonvulsant effects and neurotoxicity of the compounds were evaluated with maximal electroshock test and rotarod test. Among the synthetic compounds, 4-butyl-5-(4-(2-fluorinebenzyl)phenyl)-2H-1,2,4- triazole-3 (4H)-one (6k) was the most potent with ED50 value of 27.4 mg/kg and protective index (PI = TD50/ED50) value of 12.0. Besides the anti-MES efficacy, the potency of compound 6k against seizures induced by pentylenetetrazole (PTZ), 3-mercaptopropionic acid (3-MP), and bicuculline (BIC) was also established, which suggested that the mechanisms of action including enhancing of GABAergic activity might be involved in its anticonvulsant activity.
Synthesis, characterization and mesomorphic investigations of ester-substituted aroylhydrazones possessing a lateral hydroxyl group
Singh, Sachin Kumar,Singh, Hemant Kumar,Nandi, Rajib,Kumar, Vijay,Tarcea, Nicolae,Popp, Jürgen,Singh, Ranjan K.,Singh, Bachcha
, p. 99 - 112 (2014/04/17)
The synthesis, characterization and investigation of a new liquid crystalline series of ester containing aroylhydrazones with a lateral hydroxyl group, N-[4-(4′-alkoxy)benzoyloxy-2-hydroxy-benzylidene]-N′- [4″-alkoxybenzoyl]hydrazine (Cm,nLH), with the same or different peripheral alkoxy chains, and some of their nickel(II) and copper(II) complexes are described. All the ligands, except those with no terminal chains on either end of the molecule, exhibit an enantiotropic SmC mesophase, as evidenced by polarizing optical microscopy and differential scanning calorimetric studies. It has been found that addition of a lateral hydroxyl group along with ester-substitution to the aroylhydrazone core increases the mesomorphic as well as thermal stability of the ligands. Also, the coordination of Ni2+ and Cu2+ with the aroylhydraozone core inhibits the mesomorphic potential of the ligands. A temperature dependent Raman study of one of the members, C12,12LH (m = n = 12) has been made to identify phase transitions and to understand the molecular rearrangement as a result of changes in intermolecular interactions at the phase transition. DFT calculations have been performed to obtain the stable electronic structure of the ligand (C6,6LH) and its nickel(II) complex.
Synthesis and gelation behavior of 4′-propyl-1,1′- bi(cyclohexyl)-4-one 4-alkoxybenzoylhydrazone
Li, Juan,Chen, Pei,Chen, Xinbing,An, Zhongwei,Li, Yan
scheme or table, p. 1329 - 1330 (2011/02/17)
A series of new alkoxybenzoylhydrazones of 4′-propyl-1,1′- bi(cyclohexyl)-4-one were prepared as novel low molecular weight organogelators (LMOGs). Their gelation behaviors in 10 solvents were tested. Some of the compounds could form stable gels in bulk o
Smectic A liquid crystals from dihydrazide derivatives with lateral intermolecular hydrogen bonding
Pang, Dongmei,Wang, Haitao,Li, Min
, p. 6108 - 6114 (2007/10/03)
Six dissymmetrical dihydrazide derivatives, N-(4-alkoxybenzoyl)-N′- (4′-nitrobenzoyl) hydrazine (Cn-NO2) and N-(4-alkoxybenzoyl)- N′-(4′-biphenyl carbonyl) hydrazine (Cn-Ph), were synthesized and investigated by means of differential scanning c
Synthesis of novel discotic mesogen containing electron-transportable oxadiazole moiety
Kim, Bong Gi,Kim, Sehoon,Park, Soo Young
, p. 391 - 394 (2007/10/03)
We synthesized and characterized a novel discotic liquid crystalline material (THOB) composed of 1,3,5-tri-substituted benzene core and 2-(4-hexyloxyphenyl)-oxadiazol-5-yl arms. Chemical structure of THOB was characterized using 1H-NMR and mass spectroscopy and its thermal behavior was determined using DSC and polarized optical microscopy. THOB showed narrow mesophase region at around 128°C and exhibited nematic-like texture.
Star-shaped discotic nematic liquid crystal containing 1,3,5-triethynylbenzene and oxadiazole-based rigid arms
Kim, Bong Gi,Kim, Sehoon,Park, Soo Young
, p. 2697 - 2699 (2007/10/03)
A novel three-armed discotic liquid crystal based on 1,3,5-triethynylbenzene as a core and 2,5-diphenyloxadiazole as rigid arms has been synthesized, which is the first star-shaped molecule exhibiting a discotic nematic phase.
Synthesis and mesomorphic properties of azo compounds derived from phenyl- and thienyl-1,3,4-thiadiazole
Parra,Villouta,Vera,Belmar,Zú?iga,Zunza
, p. 1533 - 1538 (2007/10/03)
The synthesis and mesomorphic behaviour of new series of liquid crystals containing 1,3,4-thiadiazole and thiophene rings with azo central bond are reported (series 5a and 5b). All compounds of series 5a exhibit enantiotropic nematic mesophase and the hig
