64332-40-7

Upstream product

• 64332-37-2 (-)-Megaphone 
• 96851-89-7 (R)-3-((S)-2-Methoxy-3-trityloxy-propyl)-3-((S)-1-methyl-2,2-bis-methylsulfanyl-ethyl)-hex-5-en-2-one 
• 96851-88-6 (R)-2-((S)-2-Methoxy-3-trityloxy-propyl)-2-((S)-1-methyl-2,2-bis-methylsulfanyl-ethyl)-pent-4-enoic acid methyl ester 
• 96851-82-0 Lithium; (S)-5-trityloxymethyl-4,5-dihydro-furan-2-olate 
• 81952-68-3 1-lithio-3,4,5-trimethoxybenzene 
• 96851-92-2 (4R,6R)-6-Allyl-4-methoxy-6-((S)-1-methyl-2,2-bis-methylsulfanyl-ethyl)-cyclohex-2-enone 
• 72605-51-7 Lithiated 2-(3,4,5-trimethyloxyphenyl)-1,3-dithiane 
• 96851-84-2 (S)-3-Eth-(E)-ylidene-5-trityloxymethyl-dihydro-furan-2-one 
• 96851-83-1 (S)-3-Eth-(Z)-ylidene-5-trityloxymethyl-dihydro-furan-2-one 
• 96851-91-1 (2S,4R)-4-Acetyl-2-methoxy-4-((S)-1-methyl-2,2-bis-methylsulfanyl-ethyl)-hept-6-enal 
• 96851-90-0 (R)-3-((S)-3-Hydroxy-2-methoxy-propyl)-3-((S)-1-methyl-2,2-bis-methylsulfanyl-ethyl)-hex-5-en-2-one 
• 96851-93-3 (S)-2-((1R,5R)-1-Allyl-5-methoxy-2-oxo-cyclohex-3-enyl)-propionaldehyde 

Relevant academic research and scientific papers

ENANTIOSPECIFIC TOTAL SYNTHESIS OF (-)-MEGAPHONE BY A HIGHLY CONTROLLED CONSECUTIVE 1,4- AND 1,3-ASYMMETRIC INDUCTION.

Enantiospecific total synthesis of (-)-megaphone (1) is reported.The key synthetic tactic is the use of (4S)-2Z-ethylidene-4-trityloxymethyl-butan-4-olide (6) to both establish the relative and absolute stereochemistry of the contiguous tertiary and quate