643744-74-5Relevant academic research and scientific papers
Concise syntheses of substituted indolizidine alkaloids via cyclization based on α-sulfinyl carbanions: preparation of (±)-indolizidines 167B and 209D, their epimers, and (±)-tashiromine
Pohmakotr, Manat,Prateeptongkum, Saisuree,Chooprayoon, Soontorn,Tuchinda, Patoomratana,Reutrakul, Vichai
, p. 2339 - 2347 (2008/09/19)
(±)-Indolizidines 167B and 209D, their epimers and (±)-tashiromine have been successfully synthesized, starting from simple γ- or α-lactams. The strategy involves the cyclization of α-sulfinyl carbanion onto the carbonyl group of the lactam ring as the ke
A general synthetic route to 1-azabicyclo[m.n.0]alkenes via cyclisation based on α-sulfinyl carbanions
Pohmakotr, Manat,Numechai, Pornthep,Prateeptongkum, Saisuree,Tuchinda, Patoomratana,Reutrakul, Vichai
, p. 3495 - 3497 (2007/10/03)
A general synthetic route to 1-azabicyclo[m.n.0]alkenes via cyclisation based on α-sulfinyl carbanions was presented. The intramolecular nucleophillic addition of α-sulfinyl carbanions afforded 1-azabicyclo[m.n.0]alkenes in good yields. It is reported that the developed strategy should provide a general solution for the synthesis of various classes of 1-azabicyclic alkaloids.
