64379-24-4Relevant articles and documents
Process for the preparation of reactive, couplable derivatives of the thyroid hormones
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, (2008/06/13)
Process for the preparation of reactive, couplable derivatives of the thyroid hormones 3,3'',5-triiodothyronine (T 3) and 3,3'',5,5''-tetraiodothyronine (T 4) by reaction with reactive carboxylic acid derivatives, which process comprises sylylating all the functional groups of the thyroid hormone by reaction with a reactive triorganosylyl derivative and then reacting the persylylated derivative of the thyroid hormone thus obtained with an activated carboxylic acid derivative.