6440-06-8

Usage

Uses

Used in Corrosion Inhibition:
5-Mercapto-1,2,3-triazole is utilized as a corrosion inhibitor, particularly in the petroleum and oil industries. It serves to protect metal surfaces from corrosion by forming a protective film on the metal surface, thereby extending the service life of equipment and reducing maintenance costs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Mercapto-1,2,3-triazole is explored for its potential in the development of new pharmaceuticals. Its unique structure allows it to interact with biological targets, offering possibilities for the creation of novel therapeutic agents.
Used as a Chelating Agent:
5-Mercapto-1,2,3-triazole also finds application as a chelating agent in metal ion coordination chemistry. Its ability to form stable complexes with metal ions is valuable in various chemical processes and analytical techniques, enhancing the selectivity and sensitivity of metal detection and separation methods.
Used in Chemical Synthesis:
Due to its reactive thiol group and triazole ring, 5-Mercapto-1,2,3-triazole is employed as an intermediate in the synthesis of various organic and inorganic compounds. Its versatility in forming different types of chemical bonds makes it a valuable building block in the creation of complex molecules for a range of applications.

InChI:InChI=1/C2H3N3S/c6-2-1-3-5-4-2/h1H,(H2,3,4,5,6)

Downstream Products

• 37539-03-0 (6R)-7t-amino-8-oxo-3-(1H-[1,2,3]triazol-4-ylsulfanylmethyl)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 79100-69-9 5-Benzylsulfanyl-1H-[1,2,3]triazole 

Relevant academic research and scientific papers

Process for making 5-mercapto-1,2,3-triazoles

A process for making 5-mercapto-1,2,3-triazoles of the formula STR1 wherein R1 is hydrogen or a C1 -C4 -alkyl which may also be substituted, the said process comprising (1) as a first step reacting a solution of 1,2,3-thiadiazole-5-carbohydroxamic acid derivative of the formula STR2 wherein R1 has the meaning as above and R2 is hydrogen or a univalent metal equivalent in an inert organic solvent in the presence of an acid acceptor with a solution in an inert organic solvent of an acid halide of the formula so as to form an acylated 1,2,3-thiadiazole-5-carbohydroxamic acid derivative (2) reacting as a solution in an inert organic solvent the carbohydroxamic acid derivative just obtained with an alcohol or phenol of the formula so as to form a (1,2,3-thiadiazole-5-yl)-carbamic acid ester (3) then treating the thus obtained carbamic acid ester with an acetic or basic catalyst to form the 5-amino-1,2,3-thiadiazole (4) whereupon the said amino thiadiazole is subject to a rearrangement in the presence of a base followed by isolation of the product of the reaction.

7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

7-[α-(2-Aminomethyl-1-cyclohexyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids, and their nontoxic, pharmaceutically acceptable salts and their Schiff bases, as made by reaction of salicylaldehyde with the free amino group, are valuable as antibacterial agents and are particularly valuable as therapeutic agents in poultry and animals, including man, in the treatment of infectious diseases caused by many Gram-positive and Gram-negative bacteria.

7-(3-Substituted ureido) cephalosporins

Cephalosporin compounds with 3-substituted ureido or -thioureido group at position 7 and hydrogen or heterocyclicthiomethyl groups at position 3 are prepared. These compounds are antibacterial agents.