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2-(2-Methoxyphenoxy)propan-1-amine, also known as 2-(o-methoxyphenoxy)propylamine or 2-Methoxyphenoxypropylamine, is an organic compound with the chemical formula C10H15NO2. It is a colorless to pale yellow liquid with a molecular weight of 181.23 g/mol. 2-(2-methoxyphenoxy)propan-1-amine is characterized by the presence of a propylamine group (-CH2CH2CH2NH2) attached to a 2-methoxyphenoxy group (-OCH3C6H4O). It is used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity, it is typically handled under controlled conditions to prevent unwanted side reactions.

6440-87-5

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6440-87-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6440-87-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,4 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6440-87:
(6*6)+(5*4)+(4*4)+(3*0)+(2*8)+(1*7)=95
95 % 10 = 5
So 6440-87-5 is a valid CAS Registry Number.

6440-87-5Relevant academic research and scientific papers

Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors

Carocci, Alessia,Catalano, Alessia,Lovece, Angelo,Lentini, Giovanni,Duranti, Andrea,Lucini, Valeria,Pannacci, Marilou,Scaglione, Francesco,Franchini, Carlo

experimental part, p. 6496 - 6511 (2010/10/02)

A series of phenoxyalkyl and phenylthioalkyl amides were prepared as melatoninergic ligands. Modulation of affinity of the newly synthesized compound by applying SARs around the terminal amide moiety, the alkyl chain, and the methoxy group on the aromatic ring provides compounds with nanomolar affinity for both melatonin receptor subtypes. Affinity towards MT1 and MT2 receptors were modulated also exploiting chirality. The investigation of intrinsic activity revealed that all the tested compounds behave as full or partial agonists.

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