64410-44-2Relevant academic research and scientific papers
Antiviral Immunotropic Agent for the Treatment of Acute Respiratory Viral Infections
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Paragraph 0058; 0063, (2019/11/05)
The proposed methods of treatment pertain to medicine, in particular pharmacology, and concerns the application of a nasal medicinal composition containing hexapeptide tyrosyl-D-alanyl-glycyl-phenylalanyl-leucyl-arginine or its pharmaceutically acceptable
One-pot mechanosynthesis of aromatic amides and dipeptides from carboxylic acids and amines
?trukil, Vjekoslav,Bartolec, Boris,Portada, Tomislav,Dilovi?, Ivica,Halasz, Ivan,Margeti?, Davor
supporting information, p. 12100 - 12102 (2013/01/16)
Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.
Amino acids and peptides. XXIV. Preparation and antinociceptive effect of [D-Ala2, (N-Me)Phe4]enkephalin analog-poly(ethylene glycol) hybrids
Maeda,Kawasaki,Takahashi,Nakao,Kaneto
, p. 1859 - 1863 (2007/10/02)
Hybrids of amino-poly(ethylene glycol) (aPEG) and [D-Ala2,(N-Me)Phe4]enkephalin analogs, H-Tyr-D-Ala-Gly-(Me)Phe-aPEG, H-Tyr-D-Ala-Gly-(Me)Phe-Leu-aPEG and H-Tyr-D-Ala-Gly-(Me)Phe-D-Leu-aPEG, were prepared by the solution method and
Dehydro-enkephalins. Part 7. A Potent Dehydroleucine-enkephalin Resistant to Carboxypeptidase
Shimohiagashi, Yasuyuki,Stammer, Charles H.
, p. 803 - 808 (2007/10/02)
To preserve the enkephalin-like properties together with resistance to enzymatic degradation, we have synthesized unsaturated analogues of leucine enkephalin, containing dehydroleucine (ΔLeu5) in the Z-configuration (isopropyl and C=O, trans) a
Novel Analogues of Enkephalin: Identification of Functional Groups Required for Biological Activity
Gorin, Fredric A.,Balasubramanian, T. M.,Cicero, Theodore J.,Schwietzer, John,Marshall, Garland R.
, p. 1113 - 1122 (2007/10/02)
Novel tri- and tetrapeptide analogues of enkephalin, in conjunction with earlier structure-activity data, confirm that chemical substituents present in the first and fourth residues of enkephalin are required for in vitro biological activity.A class of ar
