64413-99-6Relevant academic research and scientific papers
Regioselective annulation of nitrosopyridine with alkynes: Straightforward synthesis of N-oxide-imidazopyridines
Manna, Srimanta,Narayan, Rishikesh,Golz, Christopher,Strohmann, Carsten,Antonchick, Andrey P.
, p. 6119 - 6122 (2015)
We have developed a novel method for the regioselective annulation of 2-nitrosopyridines with variably substituted alkynes under mild reaction conditions. This approach allows the annulation of alkynes with 2-nitrosopyridines under reagent- and catalyst-free reaction conditions. The developed method shows excellent functional group tolerance and provides easy access to N-oxide-imidazo[1,2-a]pyridines.
