64420-99-1

Basic information

• Product Name: 2-AMINOBIPHENYL-2',3',4',5',6'-D5
• Synonyms: 2-AMINOBIPHENYL-2',3',4',5',6'-D5;[1,1Biphenyl]-2-amine-d5;2-Aminodiphenyl-d5;2-Biphenylamine-d5;2-Phenylaniline-d5;2-Phenylbenzenamine-d5;o-Aminobiphenyl-d;o-Aminobiphenyl-D5)
• CAS NO: 64420-99-1
• Molecular Formula: C₁₂H₁₁N
• Molecular Weight: 174.25
• Product Categories: Amines;Aromatics;Isotope Labeled Compounds;Mutagenesis Research Chemicals;Isotope Labelled Compounds
• Mol File: 64420-99-1.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: 2-AMINOBIPHENYL-2',3',4',5',6'-D5(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOBIPHENYL-2',3',4',5',6'-D5(64420-99-1)
• EPA Substance Registry System: 2-AMINOBIPHENYL-2',3',4',5',6'-D5(64420-99-1)

Safety Data

• Hazardous Substances Data: 64420-99-1(Hazardous Substances Data)

Usage

Chemical Properties

Pale Yellow Oil

Uses

Has a mutagenic potency

Upstream product

• 615-36-1 2-bromoaniline 
• 215527-70-1 2,3,4,5,6-pentadeuteriumbenzeneboronic acid 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 1448169-67-2 C₂₆H₁₇⁽²⁾H₄N 
• 1312448-09-1 N-([1,1'-biphenyl]-2-yl-2',3',4',5',6'-d5)-4-methylbenzenesulfonamide 
• 1283747-68-1 2-benzenesulfonylamidobiphenyl-d₅ 

Relevant articles and documents

Electrochemical Palladium-Catalyzed Intramolecular C—H Amination of 2-Amidobiaryls for Synthesis of Carbazoles

The synthesis of carbazoles based on the electrochemical Pd-catalyzed intramolecular C—H amination of 2-amidobiaryls through oxidative cross coupling has been achieved under mild reaction conditions. The reaction can be carried out in undivided cell without the addition of external chemical oxidant. Besides good functional group compatibility, the desired carbazoles can be scaled up and modified easily. Compared with previous methods, this protocol affords a simple and sustainable avenue for the construction of carbazoles.

Palladium-Catalyzed C-H Bond Activation by Using Iminoquinone as a Directing Group and an Internal Oxidant or a Co-oxidant: Production of Dihydrophenanthridines, Phenanthridines, and Carbazoles

A palladium-catalyzed C-H bond activation reaction, via a redox-neutral pathway, for the preparation of dihydrophenanthridine, phenanthridine, and carbazole derivatives from biaryl 2-iminoquinones is developed. The preinstalled iminoquinone was designed to act as a directing group for ortho C-H activation and an internal oxidant or a co-oxidant. This catalysis proceeded through the following sequence: C-H bond activation, coordination and insertion of activated olefins, β-hydride elimination, H-shift, insertion, and protonation or β-hydride elimination. In addition, carbazoles can be prepared efficiently by using this method without the addition of external oxidants.

Synthesis of Fluorenes Starting from 2-Iodobiphenyls and CH2Br2 through Palladium-Catalyzed Dual C-C Bond Formation

A facile and efficient approach is developed for the synthesis of fluorene and its derivatives starting from 2-iodobiphenyls and CH2Br2. A range of fluorene derivatives can be synthesized under relatively mild conditions. The reaction proceeds via a tandem palladium-catalyzed dual C-C bond formation sequence through the key dibenzopalladacyclopentadiene intermediates, which are obtained from 2-iodobiphenyls through palladium-catalyzed C-H activation.