64469-10-9Relevant academic research and scientific papers
Room temperature diazotization and coupling reaction using a DES-ethanol system: A green approach towards the synthesis of monoazo pigments
Kamble, Sujit Suresh,Shankarling, Ganapati Subray
supporting information, p. 5970 - 5973 (2019/05/27)
An environmentally benign, one-pot diazotization and coupling reaction using ChCl:tartaric acid DES at room temperature is described. The bulky tartrate ion renders stability to the diazonium salt at room temperature, also evidenced by 1H NMR.
Kinetics and mechanism of gas-phase pyrolysis of N-aryl-3-oxobutanamide ketoanilides, their 2-arylhydrazono derivatives, and related compounds
Malhas, Rana N.,Al-Awadi, Nouria A.,El-Dusouqui, Osman M.E.
, p. 82 - 91 (2008/03/13)
Rates and products of reaction and Arrhenius activation parameters were determined for the gas-phase thermolysis of 14 substrates of the title compounds using sealed pyrex reactor tubes and HPLC/UV-VIS to monitor substrate pyrolysis. The 14 compounds under study are N-phenyl-3-oxo- (1), N-(p-chlorophenyl)-3-oxo- (2). N-(p-methylphenyl)-3-oxo- (3). and N-(p-methoxyphenyl)-3-oxobutanamide (4). in addition to (i) four substrates (5-8) obtained by the replacement of the pairs of methylene hydrogens at the 2-position of compounds (1-4), each pair by a phenylhydrazono group; (ii) three arylhydrazono derivatives (9-11) in which Cl, CH3, or OCH3 groups are substituted at the para position of the phenylhydrazono moiety of compound 5, (iii) 3-oxobutanamide (acetoacetamide. 12), N-phenyl-3-oxo-3- phenylpropanamide (13), and N,N′-diphenylpropanediamide (14). The reactions were conducted over 374-546 K temperature range, and the values of the Arrhenius log A(s-1) and Ea(kJ mol-1) of these reactions were, respectively, 120±2.0 and 119.2 ± 17.0 for the ketoanilides (1-4, 12-14), and 13.0 ± 0.7 and 157.5 ± 8.6 for the arylhyrazono compounds (5-11). Kinetically. the arylhydrazono derivatives were found to be ca. 1.4 × 103 to 5.7 × 103 times less reactive than the parent ketoanilides. A mechanism is proposed to account for reaction products and to rationalize molecular reactivities.
