64485-87-6Relevant articles and documents
Method for preparing ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate
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Paragraph 0026-0033; 0038-0043; 0046-0047, (2021/03/11)
The invention discloses a method for preparing an ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate. The method comprises the following steps: dissolving ethyl 2-methoxyimino acetoacetate, 1,3-dihalo-5,5-dimethylhydantoin and protonic acid in a solvent, carrying out continuous reaction, and carrying out post-treatment after the reaction is finished to obtain the ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate, wherein the ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate is 4-halo-2-methoxyimino ethyl acetoacetate. According to the method, the reaction steps are completed by adopting continuous reaction, so that the yield of the 4-halo-2-methoxyimino ethyl acetoacetate serving as the ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate can be effectively increased, the consumption of a halogenating reagent and protonic acid is reduced, and the reaction time is shortened.
The jig measuring method for measuring the shape of the film surface,
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, (2007/10/09)
PROBLEM TO BE SOLVED: To provide a fixing tool for measuring a film surface shape and a method of measuring the film surface shape for suppressing the influence of a film fixing method and the like on the measurement data to the minimum, when quantitatively measuring film surface shape. SOLUTION: The fixing tool for measuring film surface shape, being the film fixing tool used when measuring the shape of film surface or the shape of a structure formed on the film surface has: a mechanism for holding the circumference of the measuring area of the film surface from both top and bottom directions of the film; and a mechanism for pulling it in both outward directions of the XY plane of the film. Preferably, the mechanism for holding the film from both top and bottom directions of the film is so constituted that a fixing tool made of parallel flat plates holds the film from both the top and bottom. COPYRIGHT: (C)2010,JPOandINPIT