64485-87-6

Usage

Uses

Used in Agricultural Industry:
Ethyl 4-chloro-2-(methoxyimino)-3-oxobutyrate is used as an active ingredient in pesticide formulations for controlling various pests and unwanted vegetation. Its application helps in protecting crops from damage caused by these organisms, thereby ensuring a healthy and productive agricultural yield.
However, it is important to note that due to its potential toxicity to humans and the environment, ethyl 4-chloro-2-(methoxyimino)-3-oxobutyrate should be used with caution and in accordance with the recommended guidelines to minimize any adverse effects.

InChI:InChI=1/C7H10ClNO4/c1-3-13-7(11)6(9-12-2)5(10)4-8/h3-4H2,1-2H3/b9-6-

Upstream product

• 60846-14-2 2-methoxyimino-acetoacetic acid ethyl ester 

Downstream Products

• 60846-15-3 ethyl (EZ)-(2-aminothiazol-4-yl)-α-methoxyiminoacetate 

Relevant academic research and scientific papers

Method for preparing ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate

The invention discloses a method for preparing an ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate. The method comprises the following steps: dissolving ethyl 2-methoxyimino acetoacetate, 1,3-dihalo-5,5-dimethylhydantoin and protonic acid in a solvent, carrying out continuous reaction, and carrying out post-treatment after the reaction is finished to obtain the ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate, wherein the ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate is 4-halo-2-methoxyimino ethyl acetoacetate. According to the method, the reaction steps are completed by adopting continuous reaction, so that the yield of the 4-halo-2-methoxyimino ethyl acetoacetate serving as the ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate intermediate can be effectively increased, the consumption of a halogenating reagent and protonic acid is reduced, and the reaction time is shortened.

Continuous flow synthesis method of 2-(2-aminothiazole-4-yl)-2-methoxyiminoacetic acid intermediate

The invention discloses a continuous flow synthesis method of an 2-(2-aminothiazole-4-yl)-2-methoxyiminoacetic acid intermediate, and belongs to the technical field of organic synthesis. The method comprises the following steps: (1) enabling 2-methoxyimino ethyl acetoacetate to pass through a material channel A of a continuous flow microreactor, enabling sulfonyl chloride to pass through a material channel B, enabling a catalyst and an initiator to pass through a material channel C and respectively flow into a reaction channel with a preset temperature through metering pumps P1, P2 and P3 formixing reaction, and enabling reaction liquid to flow out from a discharge port after the reaction is finished; and (2) after the reaction liquid flows out, dropwise adding the reaction liquid into athiourea aqueous solution, controlling the pH value to react, adjusting the pH value to be neutral after the reaction is finished, cooling, filtering, washing and drying to obtain the 2-(2-aminothiazole-4-yl)-2-methoxyiminoacetic acid. By using the continuous flow microreactor, the continuous reaction is realized, the process is stable and easy to control, the reaction toxicity is low, the yield can reach 92.94%, and the product purity can reach 99.55%.

The jig measuring method for measuring the shape of the film surface,

PROBLEM TO BE SOLVED: To provide a fixing tool for measuring a film surface shape and a method of measuring the film surface shape for suppressing the influence of a film fixing method and the like on the measurement data to the minimum, when quantitatively measuring film surface shape. SOLUTION: The fixing tool for measuring film surface shape, being the film fixing tool used when measuring the shape of film surface or the shape of a structure formed on the film surface has: a mechanism for holding the circumference of the measuring area of the film surface from both top and bottom directions of the film; and a mechanism for pulling it in both outward directions of the XY plane of the film. Preferably, the mechanism for holding the film from both top and bottom directions of the film is so constituted that a fixing tool made of parallel flat plates holds the film from both the top and bottom. COPYRIGHT: (C)2010,JPOandINPIT