64485-92-3

Basic information

• Product Name: [6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Synonyms: [6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R)-3-[(Acetyloxy)methyl]-7α-[[[(Z)-methoxyimino][2-[(triphenylmethyl)amino]-4-thiazolyl]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• CAS NO: 64485-92-3
• Molecular Formula: C₃₅H₃₁N₅O₇S₂
• Molecular Weight: 697.77994
• EINECS: 264-914-3
• Mol File: 64485-92-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(64485-92-3)
• EPA Substance Registry System: [6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(64485-92-3)

Safety Data

• Hazardous Substances Data: 64485-92-3(Hazardous Substances Data)

Usage

Description

[6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a synthetic derivative of the antibiotic cefotaxime, belonging to the cephalosporin class of antibiotics. This complex compound exhibits potent antibacterial properties by disrupting bacterial cell wall formation, leading to bacterial destruction.

Uses

Used in Medical Applications:
[6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is used as an antibiotic for the treatment of various bacterial infections. Its effectiveness against a broad spectrum of pathogens makes it a valuable asset in modern medicine, particularly in combating drug-resistant bacteria.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is used as an active pharmaceutical ingredient (API) for the development of new antibiotics and the improvement of existing ones. Its potent antibacterial activity and versatility in chemical modification make it a promising candidate for further research and development in the fight against bacterial infections.
Used in Research and Development:
[6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[(methoxyimino)[2-(tritylamino)thiazol-4-yl]acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is also utilized in research and development for the study of bacterial resistance mechanisms, the optimization of antibiotic efficacy, and the exploration of novel drug delivery systems. Its complex structure and potent activity provide a foundation for the development of innovative therapeutic strategies in the battle against antibiotic-resistant bacteria.

Upstream product

• 121463-80-7 (6R,7R)-3-Acetoxymethyl-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 

Relevant articles and documents

Reactions of TMSI with cephalosporin esters

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