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1-(3-methoxyphenoxy)propan-2-amine, also known as 3-methoxyphenylpropanolamine, is an organic compound with the molecular formula C10H15NO2. It is a derivative of propan-2-amine, featuring a 3-methoxyphenoxy group attached to the propane chain. This chemical is characterized by its amine group, which is a primary amine, and its methoxyphenoxy group, which contributes to its unique chemical properties. It is a colorless liquid with a molecular weight of 179.23 g/mol. 1-(3-methoxyphenoxy)propan-2-amine is of interest in the field of organic chemistry and may have potential applications in the synthesis of pharmaceuticals or other chemical products due to its unique structure and reactivity.

6449-45-2

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6449-45-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6449-45-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,4 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6449-45:
(6*6)+(5*4)+(4*4)+(3*9)+(2*4)+(1*5)=112
112 % 10 = 2
So 6449-45-2 is a valid CAS Registry Number.

6449-45-2Relevant academic research and scientific papers

Design, synthesis, and pharmacological effects of structurally simple ligands for MT1 and MT2 melatonin receptors

Carocci, Alessia,Catalano, Alessia,Lovece, Angelo,Lentini, Giovanni,Duranti, Andrea,Lucini, Valeria,Pannacci, Marilou,Scaglione, Francesco,Franchini, Carlo

experimental part, p. 6496 - 6511 (2010/10/02)

A series of phenoxyalkyl and phenylthioalkyl amides were prepared as melatoninergic ligands. Modulation of affinity of the newly synthesized compound by applying SARs around the terminal amide moiety, the alkyl chain, and the methoxy group on the aromatic ring provides compounds with nanomolar affinity for both melatonin receptor subtypes. Affinity towards MT1 and MT2 receptors were modulated also exploiting chirality. The investigation of intrinsic activity revealed that all the tested compounds behave as full or partial agonists.

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