644963-89-3Relevant academic research and scientific papers
Design and synthesis of novel RXR-selective modulators with improved pharmacological profile
Michellys, Pierre-Yves,Boehm, Marcus F.,Chen, Jyun-Hung,Grese, Timothy A.,Karanewsky, Donald S.,Leibowitz, Mark D.,Liu, Sha,Mais, Dale A.,Mapes, Christopher M.,Reifel-Miller, Anne,Ogilvie, Katheen M.,Rungta, Deepa,Thompson, Anthony W.,Tyhonas, John S.,Yumibe, Nathan,Ardecky, Robert J.
, p. 4071 - 4075 (2007/10/03)
New RXR-selective modulators possessing a 6-fluoro trienoic acid moiety (6Z olefin) or a fluorinated/heterocyclic-substituted benzene core ring, were synthesized in an expedient and selective way. A subset of these compounds was evaluated for their metabo
