64500-11-4

Basic information

• Product Name: 7-bromo-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
• Synonyms: 4H-pyrido[1,2-a]pyrimidin-4-one, 7-bromo-2-methyl-
• CAS NO: 64500-11-4
• Molecular Formula: C₉H₇BrN₂O
• Molecular Weight: 239.0687
• Mol File: 64500-11-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 288.5°C at 760 mmHg
• Flash Point: 128.3°C
• Density: 1.65g/cm³
• Vapor Pressure: 0.00233mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: 7-bromo-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-bromo-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one(64500-11-4)
• EPA Substance Registry System: 7-bromo-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one(64500-11-4)

Safety Data

• Hazardous Substances Data: 64500-11-4(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 1072-97-5 5-bromo-2-pyridylamine 
• 105-45-3 acetoacetic acid methyl ester 
• 64500-14-7 N-(5-bromopyridin-2-yl)-3-oxobutanamide 
• 7664-93-9 sulfuric acid 

Relevant articles and documents

Practical synthesis of 4H-pyrido[1, 2-a]pyrimidin-4-ones using ethylene glycol as a promoting solvent

A simple and useful protocol leading to different 4H-pyrido[1, 2-a] pyrimidin-4-ones have been established by cyclization of various 2-amino pyridines with β-oxo ester or alkynoate. The use of ethylene glycol was demonstrated to facilitate this condensati

Solvent-free synthesis of 4H-Pyrido[1,2-a]pyrimidin-4-ones catalyzed by BiCl3: A green route to a privileged backbone

An extensive array of 4H-pyrido[1,2-a]pyrimidin-4-ones have been synthesized from commercially available 2-aminopyridines and β-oxo esters with excellent yields under solvent-free conditions. The reaction, catalyzed by cheap and nontoxic BiCl3,