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1,4-Naphthalenedione, 2-chloro-3-[(3-methoxyphenyl)amino]-, also known as 2-chloro-3-(3-methoxyanilino)naphthalene-1,4-dione, is a chemical compound with the molecular formula C17H13ClN2O3. It is a derivative of 1,4-naphthoquinone, featuring a chloro group at the 2-position, a methoxyphenyl group at the 3-position, and an amino group attached to the phenyl ring. 1,4-Naphthalenedione, 2-chloro-3-[(3-methoxyphenyl)amino]- is an organic molecule with potential applications in the synthesis of pharmaceuticals and other organic compounds. Its structure and properties make it a versatile intermediate in various chemical reactions, particularly in the field of medicinal chemistry.

64505-79-9

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64505-79-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 64505-79-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,5,0 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 64505-79:
(7*6)+(6*4)+(5*5)+(4*0)+(3*5)+(2*7)+(1*9)=129
129 % 10 = 9
So 64505-79-9 is a valid CAS Registry Number.

64505-79-9Relevant academic research and scientific papers

Synthesis and cytotoxicity of 6,11-Dihydro-pyrido- and 6,11-Dihydro-benzo[2,3-b]phenazine-6,11-dione derivatives

Kim, Young-Shin,Park, Se-Young,Lee, Hyun-Jung,Suh, Myung-Eun,Schollmeyer, Dieter,Lee, Chong-Ock

, p. 1709 - 1714 (2003)

6,11-Dihydro-pyrido[2,3-b]phenazine-6,11-diones and 6,11-dihydro-benzo[2,3-b]phenazine-6,11-diones were synthesized from 6,7-dichloro-5,8-quinolinedione and 2,3-dichloro-1,4-naphthoquinone. The study on the cytotoxicity on these products revealed that the pyridophenazinediones, tetracyclic heteroquinone analogues with three nitrogen atoms exhibited a high cytotoxicity on several human tumor cell lines. Compound 9c and 9e showed in vitro antitumor activity comparable or superior to doxorubicin against the human ovarian tumor cells (SK-OV-3) and the human CNS cells (XF 498). The IC50 value for compound 9e was 0.06 μM against the human CNS cells (XF 498), which was 2.6 times higher than that (0.16 μM) of doxorubicin. In addition, the X-ray crystallographic analysis of two phenazinedione derivatives (9b,c) showed clearly the exact position of the nucleophilic substitution of 6,7-dichloro-5,8-quinolinedione.

Synthesis of photoactive 1-methyl-1-R-4-(1,4-dioxo-1,4-dihydronaphthalen-2- yl)piperazinium salts

Berezhnaya,Shelkovnikov,Korotaev

experimental part, p. 1823 - 1831 (2012/03/10)

Photoactive 4-(1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperazinium salts were synthesized by alkylation of 3-chloro-2-(piperazin-1-yl)- and 2-arylamino-3-(4-methylpiperazin-1-yl)-1,4-naphthoquinones. Light sensitivities of materials obtained by adsorption o

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