645386-90-9Relevant academic research and scientific papers
Toward a Total Synthesis of Peloruside A: Enantioselective Preparation of the C8-C19 Region
Taylor, Richard E.,Jin, Meizhong
, p. 4959 - 4961 (2003)
(Equation Presented) An efficient synthetic sequence toward the C8-C19 region of peloruside A has been developed. The route is highlighted by a selective electrophilic cyclization reaction, a single-step epoxide ring-opening/methylation sequence, and a stereoselective Mukaiyama aldol reaction.
A stereoselective synthesis of the C11-C19 fragment of (+)-peloruside A
Chen, Zhen-liang,Zhou, Wei-shan
, p. 5289 - 5292 (2007/10/03)
A new route to the synthesis of the C11-C19 fragment of peloruside A is described, which includes an aldol reaction with ethyl acetoacetate, β-hydroxyl-directed reduction of β-hydroxy ketone, as well as methylation of C13 hydroxyl moiety in the system of
