6454-67-7

Basic information

• Product Name: ethyl 4-(3-trifluoromethylanilino)pyrimidine-5-carboxylate
• CAS NO: 6454-67-7
• Molecular Weight: 311.263
• Mol File: 6454-67-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-(3-trifluoromethylanilino)pyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(3-trifluoromethylanilino)pyrimidine-5-carboxylate(6454-67-7)
• EPA Substance Registry System: ethyl 4-(3-trifluoromethylanilino)pyrimidine-5-carboxylate(6454-67-7)

Safety Data

• Hazardous Substances Data: 6454-67-7(Hazardous Substances Data)

Upstream product

• 98-16-8 3-trifluoromethylaniline 
• 41103-17-7 ethyl 4-chloropyrimidine-5-carboxylate 

Downstream Products

• 6454-66-6 4-(3-trifluoromethylanilino)pyrimidine-5-carboxylic acid 

Relevant articles and documents

Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives

Spleen tyrosine kinase (Syk) is a non-receptor-type tyrosine kinase which mediates diverse responses in haematopoietic cells. Therefore, Syk is an attractive therapeutic target, and in a study of Syk inhibitors as potentially new therapeutic agents, we di