64549-36-6

Upstream product

• 1420998-29-3 4-methoxymethyl-1-methyl-2-nitro-benzene 
• 84540-59-0 4-methyl-3-nitrobenzyl chloride 

Downstream Products

• 1420998-32-8 {5-[2-(2-methoxy-imidazol-1-yl)pyridin-4-yl]oxazol-2-yl}-(5-methoxymethyl-2-methyl-phenyl)amine 
• 1420997-69-8 C₂₀H₁₉N₅O₃*ClH 
• 1420998-31-7 N-(5-methoxymethyl-2-methyl-phenyl)acetamide 

Relevant academic research and scientific papers

OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT)

The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, A, Q, W and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.