64559-91-7Relevant academic research and scientific papers
The isomerisation of (Z)-3-[2H1]-phenylprop-2-enone as a measure of the rate of hydroperoxide addition in Weitz-Scheffer and Julia-Colonna epoxidations
Kelly, David R.,Caroff, Eva,Flood, Robert W.,Heal, William,Roberts, Stanley M.
, p. 2016 - 2017 (2004)
(Z)3-[2H1]-Phenylprop-2-enone is isomerised by hydroperoxide to an equimolar mixture of the (Z)- and (E)-isomers prior to epoxidation. Poly-(L)-leucine (10 mole %) accelerates the addition of hydroperoxide by an order of magnitude an
Silver-catalyzed [2 + 2] cycloadditions of siloxy alkynes
Sweis, Randy F.,Schramm, Michael P.,Kozmin, Sergey A.
, p. 7442 - 7443 (2007/10/03)
We have described the first [2 + 2] cycloadditions of siloxy alkynes with a range of unsaturated carbonyl compounds. The reactions are efficiently promoted by substoichiometric amount of silver trifluoromethanesulfonimide and display excellent regio- and diastereoselectivity combined with a broad substrate scope. Our studies have established unambiguously the stepwise mechanism of this process and provided evidence for a novel role of silver in the catalytic cycle of the reaction, which involves silver-based complexation and activation of siloxy alkyne toward the subsequent 1,4-addition. Copyright
