64559-97-3

Basic information

• Product Name: 1(2H)-Naphthalenone, 3,4-dihydro-2-hydroxy-
• Synonyms: 2-Hydroxy-3,4-dihydro-2H-naphthalen-1-one;2-hydroxy-3,4-dihydronaphthalen-1(2H)-one;3,4-dihydro-2-hydroxynaphthalen-1(2H)-one;(+/-)-3,4-dihydro-2-hydroxy-2H-naphthalen-1-one;(+/-)-2-hydroxy-1-tetralone;3,4-dihydro-2-hydroxy-1(2H)-naphthalenone
• CAS NO: 64559-97-3
• Molecular Formula: C10H10O2
• Molecular Weight: 162.188
• Mol File: 64559-97-3.mol
• Article Data: 37

Chemical Properties

• CAS DataBase Reference: 1(2H)-Naphthalenone, 3,4-dihydro-2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Naphthalenone, 3,4-dihydro-2-hydroxy-(64559-97-3)
• EPA Substance Registry System: 1(2H)-Naphthalenone, 3,4-dihydro-2-hydroxy-(64559-97-3)

Safety Data

• Hazardous Substances Data: 64559-97-3(Hazardous Substances Data)

Upstream product

• 83022-55-3 2-hydroxy-1-tetralone dimethyl ketal 
• 38858-72-9 1-trimethylsiloxy-3,4-dihydronaphthalene 
• 197140-92-4 (-)-(S)-1,2,3,4-tetrahydro-1-oxonaphthalen-2-yl acetate 
• 41099-31-4 2-iodo-1-tetralone 
• 1402704-92-0 C₁₈H₁₃NO₃ 
• 573-57-9 1,4-epoxy-1,4-dihydronaphthalene 
• 64245-04-1 2-bromo-1-hydroxy-1,2,3,4-tetrahydronaphthalene 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 19455-84-6 3,4-dihydronaphthalen-1-yl acetate 
• 134644-00-1 methyl 2-hydroxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate 
• 18672-77-0 2-acetoxy-3,4-dihydronaphthalen-1(2H)-one 
• 784179-06-2 phosphoric acid 3,4-dihydro-naphthalen-1-yl ester diethyl ester 
• 447-53-0 1,2-Dihydronaphthalene 
• 428862-55-9 1-acetoxy-1,2-epoxytetralin 

Downstream Products

• 144101-19-9 2-((2S,4S,5S,6S)-4,5-Bis-benzyloxy-6-methyl-tetrahydro-pyran-2-yloxy)-3,4-dihydro-2H-naphthalen-1-one 
• 125132-15-2 2-((2S,4R,5S,6R)-4,5-Bis-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-3,4-dihydro-2H-naphthalen-1-one 
• 7480-36-6 (+/-)-cis-1-amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene 
• 14211-53-1 cis-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene 
• 14211-53-1 trans-naphthalene-1,2,3,4-tetrahydro-1,2-diol 

Relevant articles and documents

Enantioselective benzylation and allylation of α-trifluoromethoxy indanones under phase-transfer catalysis

The organo-catalyzed enantioselective benzylation reaction of α-trifluoromethoxy indanones afforded α-benzyl-α-trifluoromethoxy indanones with a tetrasubstituted stereogenic carbon center in excellent yield with moderate enantioselectivity (up to 57% ee). Cinchona alkaloid-based chiral phase transfer catalysts were found to be effective for this transformation, and both enantiomers of α-benzyl-α-trifluoromethoxy indanones were accessed, depended on the use of cinchonidine and cinchonine-derived catalyst. The method was extended to the enantioselective allylation reaction of α-trifluoromethoxy indanones to give the allylation products in moderate yield with good enantioselectivity (up to 76% ee).

Catalytic Enantioselective Transannular Morita-Baylis-Hillman Reaction

Catalytic and enantioselective approaches to transannular reactions are very limited and mostly are based on chiral Lewis acid catalyzed pericyclic reactions. In this report, we present an efficient and straightforward methodology to access bicyclic carbo

Divergent synthesis of N-heterocycles by Pd-catalyzed controllable cyclization of vinylethylene carbonates

Here, we report a palladium-catalyzed controllable cyclization of vinyl ethylene carbonates that proceeds through formal migration [2+3] and [5+2] cycloadditions, respectively, under mild conditions. The transformation described here affords a series of synthetically versatile 5,7-membered N-heterocycles which are found in natural products and pharmaceuticals with biological and medicinal properties.