64580-41-2

Basic information

• Product Name: 4-(BROMOMETHYL)-N-(L-METHYLETHYL)BENZAMIDE
• Synonyms: 4-(BROMOMETHYL)-N-(L-METHYLETHYL)BENZAMIDE;4-(BROMONETHYL)-N-(L-METHYLETHY)BENZAMIDE;4-(Bromomethyl)-N-(1-methylethyl)benzamide;4-(Bromomethyl)-N-isopropyl benzamide
• CAS NO: 64580-41-2
• Molecular Formula: C₁₁H₁₄BrNO
• Molecular Weight: 256.13896
• Mol File: 64580-41-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 371.7°C at 760 mmHg
• Flash Point: 178.6°C
• Appearance: /
• Density: 1.329g/cm³
• Vapor Pressure: 1.01E-05mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 4-(BROMOMETHYL)-N-(L-METHYLETHYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(BROMOMETHYL)-N-(L-METHYLETHYL)BENZAMIDE(64580-41-2)
• EPA Substance Registry System: 4-(BROMOMETHYL)-N-(L-METHYLETHYL)BENZAMIDE(64580-41-2)

Safety Data

• Hazardous Substances Data: 64580-41-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14BrNO/c1-8(2)13-11(14)10-5-3-9(7-12)4-6-10/h3-6,8H,7H2,1-2H3,(H,13,14)

Upstream product

• 52780-16-2 4-bromomethylbenzoyl chloride 
• 75-31-0 isopropylamine 
• 6232-88-8 4-bromomethylbenzoic Acid 

Relevant articles and documents

2,3-diketone indole compound, preparation method and applications thereof

The invention discloses a 2,3-diketone indole compound, a preparation method and applications thereof, wherein the compound has a structure represented by the following general formula (I) or (II). The invention further relates to a pharmaceutical composi

Discovery of novel 5-methyl-1H-pyrazole derivatives as potential antiprostate cancer agents: Design, synthesis, molecular modeling, and biological evaluation

Androgen receptor (AR) signaling functions as a core driving force for the progression of prostate cancer (PCa), and AR has been proved to be an effective therapeutic target even for castration-resistant prostate cancer (CRPC). Herein, structural modification via a fragments splicing strategy was performed based on two lead compounds T3 and 10e, leading to the discovery of a series of 5-methyl-1H-pyrazole derivatives. AR reporter gene assay revealed compounds A13 and A14 as potent AR antagonists. Some of the compounds in this series inhibited growth of PCa LNCaP cells more efficiently than enzalutamide. A13 and A14 also showed improved metabolic stability compared with 10e in human liver microsomes.