64581-17-5Relevant academic research and scientific papers
Desulfurization of 2-dialkylamino-5-phenyl-6H-1,3,4-thiadiazines to pyrazoles in acidic and alkaline media
Perova, N. M.,Egorova, L. G.,Sidorova, L. P.,Novikova, A. P.,Chupakhin, O. N.
, p. 1645 - 1651 (2007/10/03)
Pyrazoles are formed during the elimination of sulfur from 2-dialkylamino-5-phenyl-6H-1,3,4-thiadiazines with substituents at positions 2 and 6 in acidic and alkaline media. 2-Dialkylamino-1,3,4-thiadiazines are more resistant to the transformation in an acidic medium than in an alkaline medium. 2-(1-Pyrrolidinyl)thiadiazines are more resistant to the transformation, and 2-morpholino derivatives are least resistant.
