64584-26-5

Usage

Uses

Used in Pharmaceutical Industry:
N-[2-(2,5-Dimethoxyphenyl)ethyl]phthalimide is used as an intermediate in the synthesis of 2C-I, a novel psychedelic drug. It serves as a key component in the production process, contributing to the drug's psychoactive properties. N-[2-(2,5-Dimethoxyphenyl)ethyl]phthalimide is valued for its role in creating new and potentially therapeutic substances for research and medicinal purposes.

Upstream product

• 85-44-9 phthalic anhydride 
• 3600-86-0 2,5-dimethoxyphenethylamine 

Downstream Products

• 64584-29-8 2-[2-(4-iodo-2,5-dimethoxyphenyl)ethyl]isoindole-1,3-dione 

Relevant academic research and scientific papers

Bronsted acid assisted activation of imide carbonyl group: Regioselective synthesis of isoindoloisoquinolinone alkaloid (±)-nuevamine

Activation of imide carbonyl group with trifluoromethanesulfonic acid facilitates the intramolecular cyclization of phenethylphthalimides to give a fused isoindoloisoquinolinone skeleton. The first one pot regioselective synthesis of isoindoloisoquinolinone alkaloid (±)-nuevamine has been successfully executed using this methodology.

Synthesis of deuterium labeled phenethylamine derivatives

The synthesis of a series of five deuterium labeled phenethylamine derivatives, 4-bromo-2,5-[2H6]-dimethoxyphenethylamine (2C-B), 4-chloro-2,5-[2H6]-dimethoxyphenethylamine (2C-C), 2,5-[2H6]-dimethoxy-4-iodophenethylamine (2C-I), 2,5-[2H6]-dimethoxy-4-ethylthiophenethylamine (2C-T-2) and 2,5-[2H6]-dimethoxy-4-n-propylthiophenethylamine (2C-T-7) from 1,4-[2H6]-dimethoxybenzene is described. The isotopically labeled compounds are used as internal standards in gas chromatography-mass spectrometry (GC-MS) assays. Copyright