6460-67-9Relevant academic research and scientific papers
Silica sulfuric acid as a highly efficient catalyst for the synthesis of diarylacetic acids
Moore, Desiree L.,Denton, Allison E.,Kohinke, Rose M.,Craig, Brandon R.,Brenzovich, William E.
supporting information, p. 604 - 612 (2016/07/06)
ABSTRACT: An efficient heterogeneous method for the synthesis of diarylacetic acids was developed utilizing silica sulfuric acid as a catalyst. The reaction is highly efficient with a small amount of catalyst for the combination of a variety of electron-n
Taming of superacids: PVP-triflic acid as an effective solid triflic acid equivalent for Friedel-Crafts hydroxyalkylation and acylation
Prakash, G.K. Surya,Paknia, Farzaneh,Kulkarni, Aditya,Narayanan, Arjun,Wang, Fang,Rasul, Golam,Mathew, Thomas,Olah, George A.
, p. 102 - 112 (2015/03/04)
The application of poly(4-vinylpyridine) supported trifluoromethanesulfonic acid (PVP-TfOH, 1:10) as a convenient solid superacid catalyst system in Friedel-Crafts reactions is described. In the presence of PVP-TfOH, one pot solvent-free synthesis of a wide variety of diarylacetic acid derivatives was achieved by Friedel-Crafts hydroxyalkylation reaction of glyoxylic acid with arenes under mild conditions. Acylation of both activated and deactivated aromatic compounds with acetyl chloride was also achieved using PVP-TfOH complex under solvent-free conditions at room temperature. As the polymer supported triflic acid was found to be a very efficient and an easy-to-handle solid acid, it can be a useful addition to environmentally more adaptable strong acid catalyst systems.
