64604-60-0Relevant academic research and scientific papers
Potential antitumor agents: procarbazine analogs and other methylhydrazine derivatives
Beisler,Peng,Driscoll
, p. 849 - 852 (2007/10/05)
With the objective of developing new antitumor agents, two groups of hydrazine compounds, having structural features in common with the antitumor agents procarbazine and 1-acetyl-2-picolinoylhydrazine, were synthesized. The L-1210 leukemia system was used to evaluate compounds of both groups. The aliphatic procarbazines also were screened for antitumor activity as bis (benzyloxycarbonyl) derivatives and as derivatives having a phthalazine nucleus. No L-1210 antitumor activity was exhibited by these compounds.
