6464-67-1

Basic information

• Product Name: Z-Phe-Citr
• CAS NO: 6464-67-1
• Molecular Weight: 456.499
• Mol File: 6464-67-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Z-Phe-Citr(CAS DataBase Reference)
• NIST Chemistry Reference: Z-Phe-Citr(6464-67-1)
• EPA Substance Registry System: Z-Phe-Citr(6464-67-1)

Safety Data

• Hazardous Substances Data: 6464-67-1(Hazardous Substances Data)

Upstream product

• 372-75-8 Citrulline 
• 2578-84-9 N-benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester 
• 3397-32-8 N-(benzyloxycarbonyl)-phenylalanine-N-hydroxysuccinimide ester 

Downstream Products

• 448963-29-9 {(S)-1-[(S)-1-(4-Hydroxymethyl-phenylcarbamoyl)-4-ureido-butylcarbamoyl]-2-phenyl-ethyl}-carbamic acid benzyl ester 
• 97487-94-0 Carbobenzoxy-L-phenylalanyl-L-citrullin-methylester 

Relevant articles and documents

Cathepsin B-sensitive dipeptide prodrugs. 1. A model study of structural requirements for efficient release of doxorubicin

A series of lysosomal protease-sensitive peptides attached to doxorubicin (DOX) was prepared as model substrates for internalizing anticancer immunoconjugates and potential antimetastasis prodrugs. Rates of cathepsin B-mediated release of free drug was measured for each, and human plasma stabilities for representative examples.