646502-72-9Relevant articles and documents
Deletion of the Oxetane Ring in Docetaxel Analogues: Synthesis and Biological Evaluation
Deka, Vaishali,Dubois, Joelle,Thoret, Sylviane,Gueritte, Francoise,Guenard, Daniel
, p. 5031 - 5034 (2003)
(Equation presented) Two new docetaxel analogues have been prepared starting from 10-deacetylbaccatin III. Both derivatives lack the oxetane D-ring but possess the 4α-acetoxy group, which is important for biological activity. The influence of a more or le