646502-72-9

Basic information

• Product Name: Benzoic acid (1S,2S,3S,4S,7S,8S,10R)-4-acetoxy-1-hydroxy-8,12,15,15-tetramethyl-9,13-dioxo-7,10-bis-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester
• Synonyms: Benzoic acid (1S,2S,3S,4S,7S,8S,10R)-4-acetoxy-1-hydroxy-8,12,15,15-tetramethyl-9,13-dioxo-7,10-bis-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester
• CAS NO: 646502-72-9
• Molecular Weight: 743.098
• Mol File: 646502-72-9.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid (1S,2S,3S,4S,7S,8S,10R)-4-acetoxy-1-hydroxy-8,12,15,15-tetramethyl-9,13-dioxo-7,10-bis-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid (1S,2S,3S,4S,7S,8S,10R)-4-acetoxy-1-hydroxy-8,12,15,15-tetramethyl-9,13-dioxo-7,10-bis-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester(646502-72-9)
• EPA Substance Registry System: Benzoic acid (1S,2S,3S,4S,7S,8S,10R)-4-acetoxy-1-hydroxy-8,12,15,15-tetramethyl-9,13-dioxo-7,10-bis-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester(646502-72-9)

Safety Data

• Hazardous Substances Data: 646502-72-9(Hazardous Substances Data)

Upstream product

• 591-51-5 phenyllithium 
• 646502-70-7 C₃₄H₅₆O₉Si₂ 
• 646502-69-4 C₃₄H₅₅BrO₉Si₂ 
• 646502-67-2 C₃₂H₅₃BrO₈Si₂ 
• 646502-66-1 C₃₂H₅₁BrO₈Si₂ 
• 285118-31-2 2-debenzoyl-4-deacetyl-5α-bromo-7,10-di(triethylsilyl)-20-hydroxy-13-oxo-D-seco-10-deacetylbaccatin III 1,2 carbonate 

Downstream Products

• 646502-73-0 Benzoic acid (1S,2S,3S,4S,7S,8S,10R,13S)-4-acetoxy-1,13-dihydroxy-8,12,15,15-tetramethyl-9-oxo-7,10-bis-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-2-yl ester 
• 646502-75-2 2-(4-methoxy-phenyl)-4-phenyl-oxazolidine-3,5-dicarboxylic acid 5-(4-acetoxy-2-benzoyloxy-1-hydroxy-8,12,15,15-tetramethyl-9-oxo-7,10-bis-triethylsilanyloxy-tricyclo[9.3.1.0^3,8]pentadec-11-en-13-yl) ester 3-tert-butyl ester 

Relevant articles and documents

Deletion of the Oxetane Ring in Docetaxel Analogues: Synthesis and Biological Evaluation

(Equation presented) Two new docetaxel analogues have been prepared starting from 10-deacetylbaccatin III. Both derivatives lack the oxetane D-ring but possess the 4α-acetoxy group, which is important for biological activity. The influence of a more or le