646521-59-7

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-2-(hydroxymethyl)-5-(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidin yl)-, phenylmethyl ester, (2R,5R)-
• CAS NO: 646521-59-7
• Molecular Formula: C17H19N3O6
• Molecular Weight: 361.354
• Mol File: 646521-59-7.mol

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-2-(hydroxymethyl)-5-(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidin yl)-, phenylmethyl ester, (2R,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-2-(hydroxymethyl)-5-(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidin yl)-, phenylmethyl ester, (2R,5R)-(646521-59-7)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-2-(hydroxymethyl)-5-(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidin yl)-, phenylmethyl ester, (2R,5R)-(646521-59-7)

Safety Data

• Hazardous Substances Data: 646521-59-7(Hazardous Substances Data)

Upstream product

• 325771-77-5 N-(benzyloxycarbonyl)-(2R)-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(tert-butyldimethylsilyloxy)-(5R)-(tert-butyldimethylsilyloxymethyl)-aza-3-cyclopenten 

Downstream Products

• 325771-85-5 N-(9-fluorenylmethoxycarbonyl)-(2R)-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-(4S)-hydroxy-(5R)-(dimethoxytrityl-hydroxymethyl)-pyrrolidine 
• 325771-86-6 N-(9-fluorenylmethoxycarbonyl)-(2R)-(2,4-dioxo-1-methyl-1,2,3,4-tetrahydropyrimidin-5-yl)-(4S)-hydroxy-(5R)-(dimethoxytrityl-hydroxymethyl)-pyrrolidine 
• 646521-60-0 (2R,5R)-3-Hydroxy-2-hydroxymethyl-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Pyrrolidino-DNA

We synthesized pyrrolidino-C-nucleosides, incorporated them into oligodeoxynucleotides and investigated their pairing properties. The thermal duplex and triplex stabilities were measured. While triplex formation is destabilized in the case of pyrrolidino-