64675-83-8

Upstream product

• 51804-15-0 4-carboxyphenyl 4-methylbenzenesulfonate 
• 98-59-9 p-toluenesulfonyl chloride 
• 99-96-7 4-hydroxy-benzoic acid 

Downstream Products

• 64467-74-9 1-{2-propyl-1-[4-(toluene-4-sulfonyloxy)-benzoyl]-indolizin-3-yl}-ethanone 
• 1375957-29-1 4-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-30-4 4-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl-4-methylbenzenesulfonate ⁽²⁾ and 2-(4-(tosyloxy)benzamido) benzoic acid 
• 1375957-46-2 4-(3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-47-3 4-(3-(4-chlorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-31-5 4-(4-oxo-2-(4-(tosyloxy)phenyl) quinazolin-3(4H)-yl) benzoic acid 
• 1375957-32-6 4-(3-(4-acetylphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-48-4 (E)-4-(3-(4-cinnamoylphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-49-5 (E)-4-(3-(4-(3-(4-methoxyphenyl)acryloyl)phenyl)-4-oxo-3,4-dihydroquinazolin-2-yl) phenyl 4-methylbenzenesulfonate 
• 1375957-50-8 (E)-4-(4-oxo-3-(4-(3-(p-tolyl)acryloyl)phenyl)-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-51-9 4-(4-oxo-3-(4-(5-phenyl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-52-0 4-(3-(4-(5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-53-1 4-(4-oxo-3-(4-(5-(p-tolyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 
• 1375957-33-7 4-(4-oxo-3-(thiazol-2-yl)-3,4-dihydroquinazolin-2-yl)phenyl-4-methylbenzenesulfonate 

Relevant academic research and scientific papers

Aromatic-ring azacyclo derivatives and application thereof

Aromatic-ring azacyclo derivatives and an application thereof are provided. The invention relates to compounds represented by the formula (V), and a preparation method and an application thereof in medicines. In particular, the invention relates to derivatives of the compounds represented by the general formula (V), and a preparation method and the application thereof as therapeutic agents in prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, type-II diabetes, hyperglycemia, obesity or insulin resistance syndromes and metabolic syndromes. The compounds disclosed by the invention also can reduce total cholesterol, LDL-cholesterol and triglycerides, increase the expression of hepatic LDL receptors and inhibit the expression of PCSK9.

Novel quinazolinone derivatives: Synthesis and antimicrobial activity

4-(4-Oxo-4H-3,1-benzoxazin-2-yl)phenyl-4-methylbenzenesulfonate (2) was prepared and reacted with some primary aromatic amines, e.g., aniline, p-chloro aniline, p-methoxy aniline, p-amino benzoic acid and p-amino acetophenone. It reacted also with some he

A process for preparing benzo[b]thiophene derivatives

The present invention relates in general to the field of organic chemistry, and in particular to the preparation of benzo[b]thiophene derivatives. These benzo[b]thiophene derivatives are useful as intermediates in the synthesis of pharmaceutically active agents such as raloxifene or derivatives thereof.

A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES

The present invention relates in general to the field of organic chemistry, and in particular to the preparation of benzo[b]thiophene derivatives. These benzo[b]thiophene derivatives are useful as intermediates in the synthesis of pharmaceutically active agents such as raloxifene or derivatives thereof.