6468-44-6Relevant academic research and scientific papers
Zn(II)-Catalyzed One-Pot Synthesis of Coumarins from Ynamides and Salicylaldehydes
Yoo, Huen Ji,Youn, So Won
, p. 3422 - 3426 (2019/05/10)
A highly efficient and straightforward synthesis of diversely substituted coumarins from ynamides and salicylaldehydes in the presence of Zn(II) catalyst has been developed. The sulfonamide moiety of ynamides was successfully recycled in this process, serving as an effective traceless directing group for high regioselectivity in the bond-forming event. The advantages of this protocol are good functional group tolerance, broad substrate scope, simple and high-yielding reaction, recovery/reuse of the sulfonamides, low catalyst loading of inexpensive catalyst, and, by these merits, a more cost-effective and greener process.
Palladium-catalyzed decarboxylative cross-coupling reactions: A route for regioselective functionalization of coumarins
Jafarpour, Farnaz,Zarei, Samaneh,Olia, Mina Barzegar Amiri,Jalalimanesh, Nafiseh,Rahiminejadan, Soraya
, p. 2957 - 2964 (2013/06/05)
A straightforward, regioselective, and step-economical ligand-free palladium-catalyzed decarboxylative functionalization of coumarin-3-carboxylic acids is devised. This protocol is compatible with a wide variety of electron-donating and -withdrawing substituents and allows for construction of various biologically important π-electron extended coumarins.
