64681-74-9

Upstream product

• 138366-30-0 (1S,4S,5R,8S)-4-Isopropyl-8-(4-methoxy-benzyloxymethyl)-1,7-dimethyl-bicyclo[3.2.1]oct-6-ene-6-carbaldehyde 
• 138366-27-5 tert-Butyl-[(1R,4S,5S,6S,7R,8S)-4-isopropyl-8-(4-methoxy-benzyloxymethyl)-1,7-dimethyl-bicyclo[3.2.1]oct-6-ylmethoxy]-dimethyl-silane 
• 138366-21-9 (1S,2S,5R,6R,7R,8S)-8-Benzyloxy-7-(tert-butyl-dimethyl-silanyloxymethyl)-2-isopropenyl-5,6-dimethyl-bicyclo[3.2.1]octan-2-ol 
• 138366-22-0 ((1S,4R,5R,6S,7S,8R)-8-Benzyloxy-4-isopropenyl-4-methoxy-1,7-dimethyl-bicyclo[3.2.1]oct-6-ylmethoxy)-tert-butyl-dimethyl-silane 
• 138366-19-5 (1R,5S,6R,7R,8S)-8-Benzyloxy-1,7-dimethyl-4-oxo-bicyclo[3.2.1]octane-6-carboxylic acid ethyl ester 
• 138366-19-5 (1R,5S,6S,7R,8S)-8-Benzyloxy-1,7-dimethyl-4-oxo-bicyclo[3.2.1]octane-6-carboxylic acid ethyl ester 
• 138366-17-3 (2S,5R,6R,8S)-6-Hydroxy-2-methoxymethoxy-5,8-dimethyl-tricyclo[3.2.1.0^2,7]octane-1-carboxylic acid ethyl ester 
• 138366-24-2 (1R,4S,5S,6R,7R,8S)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-4-isopropyl-1,7-dimethyl-bicyclo[3.2.1]octan-8-ol 
• 138366-25-3 C₂₁H₄₀O₂Si 
• 138366-20-8 (1S,5R,6R,7R,8S)-8-Benzyloxy-7-(tert-butyl-dimethyl-silanyloxymethyl)-5,6-dimethyl-bicyclo[3.2.1]octan-2-one 
• 138366-18-4 (2S,5R,6R,8S)-6-Benzyloxy-2-methoxymethoxy-5,8-dimethyl-tricyclo[3.2.1.0^2,7]octane-1-carboxylic acid ethyl ester 
• 138366-29-7 (1S,2R,5R,6R,8R)-2-Isopropyl-8-(4-methoxy-benzyloxymethyl)-5,6-dimethyl-7-methylene-bicyclo[3.2.1]octan-6-ol 
• 138366-16-2 2-Methoxymethoxy-5,8-dimethyl-6-oxo-tricyclo[3.2.1.0^2,7]octane-1-carboxylic acid ethyl ester 
• 138366-28-6 (1R,4S,5R,7R,8S)-4-Isopropyl-8-(4-methoxy-benzyloxymethyl)-1,7-dimethyl-6-methylene-bicyclo[3.2.1]octane 

Downstream Products

• 723-61-5 (+/-)-helminthosporal 
• 723-61-5 (+/-)-epihelminthosporal 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF (+/-)-HELMINTHOSPORAL VIA FRAGMENTATION REACTION

A new route for the total synthesis of (+/-)-helminthosporal ((+/-)-1), involving fragmentation reaction of tricyclo2,7>octane derivative 5 to give bicyclooctane derivative 6 as a crucial step, is described.