647-42-7Relevant articles and documents
Further evidence on the importance of fluorous-fluorous interactions in supramolecular chemistry: A combined structural and computational study
Omorodion, Harrison,Twamley, Brendan,Platts, James A.,Baker, Robert J.
, p. 2835 - 2841 (2015)
The solid-state structures of CF3(CF2)5CH2CO2H and a fluorous triazole are reported, both of which display a wide variety and large number of noncovalent interactions in their packing. The solid-state structure of CF3(CF2)5CH2CO2H is stabilized by multiple F···F contacts but only one C-H···F-C interaction, as well as O-H···O and C-H···O hydrogen bonds. In contrast to other reported structures, the torsion angles in the fluorous chain are close to 180°, which means that the fluorine atoms are eclipsed. A DFT study of the interactions in both compounds show that F···F interactions, along with stacking and C-H···F and C-H···O contacts, are individually weakly energetically stabilizing, but collectively, they can give rise to interaction energies of up to 13 kcal mol-1. A topological approach to the interactions using atoms-in-molecules (AIM) theory reveals that there are bond critical points between the C-F···F-C interactions as well as C-F···H-C interactions that are not recognized when using only the van der Waals distances.
Method for preparing perfluoroalkyl ethanol
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Paragraph 0026-0032, (2017/11/29)
The invention discloses a method for preparing perfluoroalkyl ethanol. The method comprises the following steps: enabling perfluoroalkyl ethyl iodide, a mixed solvent and water to react, and separating and purifying the obtained mixture containing perfluoroalkyl ethanol, by-product olefins, solvent salt and water, thereby obtaining the perfluoroalkyl ethanol product, wherein the separation and purification comprise the following steps: (1) adding a mixture containing perfluoroalkyl ethanol, by-product olefins, solvent salt and water into a rectifying tower for performing reduced pressure distillation, controlling the vacuum degree to be -0.91 to -0.96MPa so as to obtain distillate containing perfluoroalkyl ethanol, by-product olefins and water and bottom liquid, performing strong base treatment on the bottom liquid, and filtering to obtain the recycled mixed solvent; and (2) performing azeotropic distillation on the distillate, thereby obtaining the mixed solution of the by-product olefins and water and the product perfluoroalkyl ethanol. The method disclosed by the invention has the advantages of simplicity in process, greening, environment friendliness, convenience, high efficiency and low cost.
Method for preparing perfluoroalkyl alcohol from perfluoroalkyl ethylene
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Paragraph 0026; 0028; 0029, (2017/04/03)
The invention discloses a method for preparing perfluoroalkyl alcohol from perfluoroalkyl ethylene.The method comprises the main steps that 1, a borane tetrahydrofuran solution is dropwise added into a dry three-opening bottle containing a perfluoroalkyl vinyl ether solution under the protection of nitrogen atmosphere; the mixture is stirred at the temperature of -20-25 DEG C, the reaction time is 8-24 h, after the reaction is finished, deionized water is added to decompose unreacted borane, and a reaction intermediate product is obtained; 2, inorganic strong base and a hydrogen peroxide aqueous solution are added into the reaction intermediate product, a reaction is performed for 0.5-3 h at the temperature of 0-50 DEG C, a solvent is removed after the reaction is finished, deionized water is used for washing, liquid separation is carried out, anhydrous magnesium sulfate is used for drying, and the perfluoroalkyl alcohol is prepared.The technological method is easy, the reaction can be performed under the normal pressure, the raw materials are rich and easy to obtain, the reaction efficiency is 100%, the yield is larger than 75%, and the method is suitable for industrial production.