64705-40-4

Upstream product

• 144151-89-3 1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-6-oxo-2,3,3a,4,5,6-hexahydro-1H-indole-7-carboxylic acid ethyl ester 
• 144039-63-4 1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-6-oxo-2,3,3a,4,5,6-hexahydro-1H-indole-7-carboxylic acid tert-butyl ester 
• 90408-66-5 3-(N-β-bromoethyl-N-3,4-dimethoxyphenethyl)aminocyclohex-2-en-1-one 
• 40173-90-8 3,4-dimethoxyphenethyl bromide 
• 90408-65-4 N-(3,4-dimethoxyphenethyl)aziridine 
• 144039-61-2 1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-pyrrolidine-2-thione 
• 144151-92-8 [1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-pyrrolidin-(2E)-ylidene]-acetic acid ethyl ester 
• 144151-83-7 3-{1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-2-oxo-pyrrolidin-3-yl}-propionic acid ethyl ester 
• 144151-85-9 3-{1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-2-thioxo-pyrrolidin-3-yl}-propionic acid ethyl ester 
• 144151-87-1 3-{1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-2-[1-ethoxycarbonyl-meth-(E)-ylidene]-pyrrolidin-3-yl}-propionic acid ethyl ester 
• 144313-43-9 1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-4-(2-ethoxycarbonyl-ethyl)-5-(2-ethoxycarbonyl-ethylsulfanyl)-3,4-dihydro-2H-pyrrolium; bromide 

Relevant academic research and scientific papers

Synthesis of Hexahydroindol-6-ones by Cycloacylation of Vinylogous Urethanes

The title compounds were prepared by variations of a route in which the principal stages include conversion of N-substituted pyrrolidine-2-thiones 6 into vinylogous urethanes 10, which undergo subsequent cycloacylation.A related approach that uses a Robin

Synthesis of hexahydroindol-6-ones by reaction of 2-methylthiopyrrolinium salts with Nazarov reagents

The title compounds 6-8 were prepared by variations of a route commencing with base-promoted condensation of N-substituted 2-methylthio-Δ1-pyrrolinium iodides 2 with Nazarov and related reagents, followed by further manipulation of substituted enamines 11-14.

AZIRIDINE IN ALKALOID SYNTHESIS. vi. ALTERNATIVE SYNTHETIC APPROACH TO THE BASIC SKELETON OF ERYTHRINA ALKALOIDS

Treatment of the aziridine (2) with 3-bromocyclohex-2-en-1-one afforded the bromo derivative (4), which was then thermally cyclized to give the enaminone (8) siteselectively.Reaction of 10 with mercuric acetate furnished 12 instead of the desired erythria