6475-05-4Relevant academic research and scientific papers
Unified total syntheses of structurally diverse akuammiline alkaloids
Xie, Xiaoni,Wei, Bei,Li, Guang,Zu, Liansuo
, p. 5430 - 5433 (2017)
The unified total syntheses of structurally diverse akuammiline alkaloids deformylcorymine (1), strictamine (2), and calophyline A (3) are reported. The strategy mimics the biosynthesis in nature at a strategic level, which allows for structural diversification from a common synthetic precursor by late-stage ring migrations.
Enantioselective Total Syntheses of Akuammiline Alkaloids (+)-Strictamine, (-)-2(S)-Cathafoline, and (-)-Aspidophylline A
Moreno, Jesus,Picazo, Elias,Morrill, Lucas A.,Smith, Joel M.,Garg, Neil K.
supporting information, p. 1162 - 1165 (2016/02/18)
The akuammiline alkaloids are a family of natural products that have been widely studied for decades. Although notable synthetic achievements have been made recently, akuammilines that possess a methanoquinolizidine core have evaded synthetic efforts. We report an asymmetric approach to these alkaloids, which has culminated in the first total syntheses of (-)-2(S)-cathafoline and the long-standing target (+)-strictamine. Moreover, the first enantioselective total synthesis of aspidophylline A is described.
Constituents of Alstonia scholaris R.Br. - Conversion of Picrinine into Strictamine & to a Pyrrolidinoindolenine System
Banerji, J.,Chakrabarti, R.
, p. 453 - 454 (2007/10/02)
Picrinine (1), a major alkaloid of Alstonia scholaris has been converted into strictamine (2), a minor alkaloid of Rhazya stricta Decaisne, as well as to a rearranged pyrrolidinoindolenine system.
