64754-67-2

Upstream product

• 5413-05-8 ethyl 2-phenylacetoacetate 
• 1155802-39-3 3-isopropoxy-5-methyl-4-phenyl-1H-pyrazole 
• 16648-44-5 methyl α-acetylphenylacetate 
• 101-41-7 benzeneacetic acid methyl ester 

Downstream Products

• 60848-28-4 3-methyl-4-phenyl-4-chloro-2-pyrazolin-5-one 
• 852470-56-5 1-(3-hydroxy-5-methyl-4-phenylpyrazol-1-yl)ethanone 
• 1068515-64-9 3-methyl-4-phenyl-1-(pyridin-2-yl-methyl)-1H-pyrazol-5-ol 

Relevant academic research and scientific papers

PYRAZOLONE DERIVATIVES AS NITROXYL DONORS

The disclosed subject matter provides pyrazolone derivative compounds, pharmaceutical compositions comprising such compounds, kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.

Alkoxypyrazoles and the process for their preparation

The present invention relates to a alkoxypyrazoles preparation process, and new alkoxypyrazole compounds.

4-Arylation of 3-alkoxypyrazoles

Following the study of the alkoxypyrazoles nitrogen's reactivity toward arylation or alkylation reactions, we report here our results on the introduction of various aryl groups on carbon 4 position of 3-alkoxypyrazoles. This was achieved from the correspo

PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS

This invention is directed to pyrazole and pyrrole compounds, for example, compounds of formula (I): wherein R1, R2, R3 and R4 are as defined herein, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment of iron disorders. This invention is also directed to pharmaceutical compositions comprising the compounds and methods of using the compounds to treat iron disorders.